Kawai N, Sotobata I, Okada M, Iwase M, Yamamoto S, Matsushima H, Miyakoda H, Yokota M, Yamauchi K, Hayashi H
Jpn Heart J. 1985 Sep;26(5):767-75. doi: 10.1536/ihj.26.767.
Myocardial involvement in progressive muscular dystrophy of the Duchenne type was evaluated in 19 patients using thallium-201 myocardial perfusion imaging. A qualitative analysis was performed from five projection images by three experienced physicians. Distinct perfusion defects were shown in 13 patients, especially in the LV posterolateral or posterior wall (11 patients). There was no significant relationship between the presence of perfusion defects and the skeletal muscle involvements or thoracic deformities assessed by transmission computed tomography. Extensive perfusion defects were shown in 2 patients who died of congestive heart failure 1 to 2 years after the scintigraphic study. Progression of the myocardial scintigraphic abnormalities were considered to be minimal in 7 of 9 patients who underwent two serial scintigraphic studies over 2 to 3 years. It was concluded that thallium myocardial perfusion imaging is a useful clinical technique to assess myocardial involvement in Duchenne's progressive muscular dystrophy.
采用铊-201心肌灌注显像技术对19例杜兴型进行性肌营养不良患者的心肌受累情况进行了评估。由三位经验丰富的医生从五个投影图像进行定性分析。13例患者出现明显的灌注缺损，尤其是左心室后外侧壁或后壁（11例患者）。灌注缺损的存在与通过透射计算机断层扫描评估的骨骼肌受累或胸廓畸形之间无显著相关性。在闪烁扫描研究后1至2年死于充血性心力衰竭的2例患者中显示有广泛的灌注缺损。在2至3年期间接受两次连续闪烁扫描研究的9例患者中，有7例患者的心肌闪烁扫描异常进展被认为是最小的。结论是，铊心肌灌注显像是评估杜兴进行性肌营养不良患者心肌受累情况的一种有用的临床技术。
