Bentourqi Mohammed, Moukhlissi Mohamed, Bouabid Meriem, Slimani Oussama, BenSghier Ahmed, Berhili Soufiane, Mezouar Loubna
Radiation Oncology, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR.
Cureus. 2025 Jul 26;17(7):e88804. doi: 10.7759/cureus.88804. eCollection 2025 Jul.
While meningiomas are the most frequent among adult primary intracranial tumors, they remain a rare condition in children, accounting for less than 5% of pediatric central nervous system tumors. These tumors have been linked to conditions like neurofibromatosis type 2 and radiation exposure, and they usually present with increased intracranial pressure and other neurological symptoms. Diagnosis relies on magnetic resonance imaging (MRI), which reveals heterogeneous masses often mistaken for other types of tumors. Surgical resection is the first line of treatment; however, it is often complicated by anatomical characteristics and the fast growth rate of pediatric meningiomas. Adjuvant radiotherapy is commonly used in high-grade or residual meningiomas. Histopathological evaluation is essential to determine the grade and subtype of the meningioma, which in turn influences the prognosis and clinical management. The case involves a five-year-old boy suffering from a large atypical meningioma, managed successfully by complete surgical resection followed by radiotherapy. This scenario underscores the significance of integrated therapeutic modalities that bring together surgery and radiotherapy for better long-term control over the disease in children with meningioma cases.
虽然脑膜瘤是成人原发性颅内肿瘤中最常见的，但在儿童中仍然是一种罕见疾病，占小儿中枢神经系统肿瘤的比例不到5%。这些肿瘤与2型神经纤维瘤病和辐射暴露等情况有关，通常表现为颅内压升高和其他神经症状。诊断依赖于磁共振成像（MRI），其显示的异质性肿块常被误诊为其他类型的肿瘤。手术切除是一线治疗方法；然而，小儿脑膜瘤的解剖特征和快速生长速度常常使手术复杂化。辅助放疗常用于高级别或残留脑膜瘤。组织病理学评估对于确定脑膜瘤的分级和亚型至关重要，这反过来又会影响预后和临床管理。该病例涉及一名患有大型非典型脑膜瘤的五岁男孩，通过完整手术切除并随后进行放疗成功治疗。这种情况强调了综合治疗模式的重要性，即将手术和放疗结合起来，以便更好地长期控制儿童脑膜瘤病例的疾病。
