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输尿管镜检查治疗肾结石后单J型与双J型支架的比较:安全性和耐受性的随机对照研究

Single-J versus double-J stents after ureterorenoscopy for renal stones: A randomized comparison of safety and tolerability.

作者信息

Tinoco Catarina Laranjo, Martins Luis, Costa Francisca, Cardoso Andreia, Araújo Ana Sofia, Capinha Mariana, Pinto Luis, Coutinho Aparício, Oliveira Carlos, Marques Vera, Torres Joao Pimentel, Mota Paulo

机构信息

Department of Urology, Hospital de Braga, Braga, Portugal.

School of Medicine, University of Minho, Braga, Portugal.

出版信息

Cent European J Urol. 2025;78(2):192-198. doi: 10.5173/ceju.2024.0212. Epub 2025 May 8.

Abstract

INTRODUCTION

Ureteral stents are generally used after ureterorenoscopy (URS) procedures, even in uncomplicated ones. We aimed to compare the safety and tolerability of single-J (SJ) stents and double-J (DJ) stents in patients submitted to flexible URS for renal stones.

MATERIAL AND METHODS

This prospective, randomized, unblinded, single-center study was conducted between July 2022 and May 2024, involving patients undergoing flexible URS with holmium laser lithotripsy for renal stones. Patients were randomized to either SJ stents (removed within 24 hours) or DJ stents (removed 2-4 weeks post-surgery). Primary endpoints included emergency department admissions, postoperative complications, and reintervention rates. Secondary endpoints included stent tolerability and surgery efficacy. A symptom questionnaire was applied at postoperative weeks 1 (W1) and 4 (W4).

RESULTS

We included 125 patients (60 in group SJ and 65 in group DJ), with comparable baseline characteristics. Emergency department admissions were similar (18.3% vs 16.9%, p = 0.84), as were complications (18.3% vs 21.5%, p = 0.65) and reintervention rates (1.7% vs 3.1%, p = 1.0). SJ stents showed better tolerability, with lower scores for lower urinary tract symptoms (LUTS) and pain at both time points.

CONCLUSIONS

SJ stents placed for less than 24 hours after complete flexible URS are comparable to DJ stents regarding safety and are better tolerated, particularly 4 weeks after the surgery. SJ stents should be prioritized, reducing costs and hospital visits for stent removal.

摘要

引言

输尿管支架通常在输尿管肾镜检查(URS)术后使用,即使是在无并发症的手术中。我们旨在比较单J(SJ)支架和双J(DJ)支架在接受软性URS治疗肾结石患者中的安全性和耐受性。

材料与方法

本前瞻性、随机、非盲、单中心研究于2022年7月至2024年5月进行,纳入接受软性URS联合钬激光碎石术治疗肾结石的患者。患者被随机分为SJ支架组(术后24小时内取出)或DJ支架组(术后2 - 4周取出)。主要终点包括急诊科就诊情况、术后并发症和再次干预率。次要终点包括支架耐受性和手术疗效。在术后第1周(W1)和第4周(W4)应用症状问卷。

结果

我们纳入了125例患者(SJ组60例,DJ组65例),基线特征具有可比性。急诊科就诊情况相似(18.3%对16.9%,p = 0.84),并发症情况(18.3%对21.5%,p = 0.65)和再次干预率(1.7%对3.1%,p = 1.0)也相似。SJ支架显示出更好的耐受性,在两个时间点下尿路症状(LUTS)和疼痛评分更低。

结论

在完全软性URS术后放置少于24小时的SJ支架在安全性方面与DJ支架相当,并且耐受性更好,尤其是在术后4周。应优先选择SJ支架,以降低成本和减少支架取出的医院就诊次数。

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