Yoon June Hyeok, An Su Hyun, Kim Yangsu, Kim Hyeon-Jin, Kong Changsu
Department of Animal Science and Biotechnology, Kyungpook National University, Sangju 37224, Korea.
Research Institute for Innovative Animal Science, Kyungpook National University, Sangju 37224, Korea.
J Anim Sci Technol. 2025 Jul;67(4):817-825. doi: 10.5187/jast.2024.e49. Epub 2025 Jul 31.
A novel granulated L-methionine (Met) has been developed using a simplified purification process, however its replacement with DL-Met has not yet been explored. The objective of the present study was to investigate the growth performance of broilers fed diets containing granulated L-Met (90% purity) compared to a diet containing DL-Met (99% purity). A total of 192 one-day-old broilers were allocated in four dietary treatments with six replicates (eight birds/cage) in a randomized complete block design based on body weight as the blocking factor. Twelve experimental diets were used, with four for each of the three growth stages: pre-starter (day 0 to 7), starter (day 7 to 21), and grower (day 21 to 28). The experimental diets consisted of: (1) a diet containing DL-Met at 100% of the digestible Met requirement, (2) a diet containing granulated L-Met at 85% of the digestible Met requirement, (3) a diet containing granulated L-Met at 90% of the digestible Met requirement, and (4) a diet containing granulated L-Met at the same inclusion rate (approximately 95% of the digestible Met requirement) as diet 1. The broilers were fed experimental diets during the pre-starter, starter, and grower stages, and growth performance was recorded by correcting mortality throughout the experiment period. Over the entire 28-day period, body weight gain and feed intake of broilers fed diets containing granulated L-Met increased linearly ( < 0.05) with an increase in dietary granulated L-Met supplementation. However, the growth performance of broilers fed diets containing granulated L-Met did not differ from those fed a diet containing DL-Met. The bioefficacy of L-Met relative to DL-Met for body weight gain and gain-to-feed ratio during the pre-starter stage was 116.9% and 104.0%, respectively. During the starter stage, the bioefficacy of L-Met relative to DL-Met was 127.5% and 111.0% for body weight gain and gain-to-feed ratio, respectively. Results of the present study reveal that the growth performance of broilers fed diets containing granulated L-Met was comparable to those fed a diet containing DL-Met, despite the lower dietary Met intake than digestible Met requirement. This suggests that L-Met might exhibit greater bioefficacy relative to DL-Met.
一种采用简化提纯工艺研制的新型颗粒状L-蛋氨酸（Met）已问世，然而其替代DL-蛋氨酸的情况尚未得到研究。本研究的目的是调查与饲喂含DL-蛋氨酸（纯度99%）日粮的肉鸡相比，饲喂含颗粒状L-蛋氨酸（纯度90%）日粮的肉鸡的生长性能。总共192只1日龄肉鸡按体重作为区组因素，采用随机完全区组设计分配到四种日粮处理组，每组六个重复（每笼八只鸡）。使用了12种试验日粮，三个生长阶段各四种：预启始期（第0至7天）、启始期（第7至21天）和生长期（第21至28天）。试验日粮包括：（1）一种含100%可消化蛋氨酸需求量的DL-蛋氨酸的日粮，（2）一种含85%可消化蛋氨酸需求量的颗粒状L-蛋氨酸的日粮，（3）一种含90%可消化蛋氨酸需求量的颗粒状L-蛋氨酸的日粮，以及（4）一种含与日粮1相同添加率（约95%可消化蛋氨酸需求量）的颗粒状L-蛋氨酸的日粮。肉鸡在预启始期、启始期和生长期饲喂试验日粮，并在整个试验期通过校正死亡率记录生长性能。在整个28天期间，饲喂含颗粒状L-蛋氨酸日粮的肉鸡的体重增加和采食量随日粮颗粒状L-蛋氨酸添加量的增加呈线性增加（<0.05）。然而，饲喂含颗粒状L-蛋氨酸日粮的肉鸡的生长性能与饲喂含DL-蛋氨酸日粮的肉鸡没有差异。在预启始期，L-蛋氨酸相对于DL-蛋氨酸在体重增加和料重比方面的生物效价分别为116.9%和104.0%。在启始期，L-蛋氨酸相对于DL-蛋氨酸在体重增加和料重比方面的生物效价分别为127.5%和111.0%。本研究结果表明，尽管日粮蛋氨酸摄入量低于可消化蛋氨酸需求量，但饲喂含颗粒状L-蛋氨酸日粮的肉鸡的生长性能与饲喂含DL-蛋氨酸日粮的肉鸡相当。这表明相对于DL-蛋氨酸，L-蛋氨酸可能具有更高的生物效价。
