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[静脉注射异丙肾上腺素试验在诊断缺血性心脏病中的重要性]

[Importance of the intravenous isoprenaline test in diagnosing ischemic heart disease].

作者信息

Khafizov R M, Sidorenko B A

出版信息

Kardiologiia. 1985 Nov;25(11):50-4.

PMID:4087672
Abstract

The isoprenaline test was performed in 89 patients with CHD and cardialgias of various origins. The diagnosis was verified by coronarography and bicycle ergometry in 60 patients. Isoprenaline was administered via intravenous drip, with the initial rate of 2-3 micrograms/min eventually increased until clinical or electrocardiographic signs of myocardial ischemia emerged, or the heart rate reached 130 beats per minute. When compared with coronarographic and bicycle-ergometric results, the isoprenaline test was shown to be highly sensitive and specific (64.3 and 95.2%), as evidenced by the electrocardiographic positive-result criteria, and superior to bicycle ergometry in its diagnostic possibilities. The isoprenaline test is recommended for the diagnosis of coronary heart disease in cardiologic and therapeutic hospital units. The test can be a method of choice in cases where rationed exercise tests are impossible to achieve.

摘要

对89例患有冠心病及各种原因引起的心前区疼痛的患者进行了异丙肾上腺素试验。60例患者通过冠状动脉造影和自行车测力计验证了诊断结果。异丙肾上腺素通过静脉滴注给药,初始速率为2 - 3微克/分钟,最终逐渐增加,直至出现心肌缺血的临床或心电图征象,或心率达到每分钟130次。与冠状动脉造影和自行车测力计的结果相比,异丙肾上腺素试验显示出高度的敏感性和特异性(分别为64.3%和95.2%),这由心电图阳性结果标准证明,并且在诊断可能性方面优于自行车测力计。建议在心脏病学和治疗医院单位使用异丙肾上腺素试验来诊断冠心病。在无法进行定量运动试验的情况下,该试验可以作为一种首选方法。

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