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通过SleepNet整合生理信号以增强睡眠呼吸暂停诊断

Integrating physiological signals for enhanced sleep apnea diagnosis with SleepNet.

作者信息

Hemrajani Prashant, Dhaka Vijaypal Singh, Rani Geeta, Verma Sahil, Woźniak Marcin, Shafi Jana, Ijaz Muhammad Fazal

机构信息

Computer and Communication Engineering, Manipal University Jaipur, Jaipur, Rajasthan, 303007, India.

Department of CSE, Rayat Bahra University, Mohali, Punjab, India.

出版信息

Sci Rep. 2025 Aug 28;15(1):31715. doi: 10.1038/s41598-025-16154-7.

DOI:10.1038/s41598-025-16154-7
PMID:40877360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12394614/
Abstract

Sleep apnea, a prevalent respiratory disorder, poses significant health risks, including cardiovascular complications and behavioral issues, if left untreated. Traditional diagnostic methods like polysomnography, although effective, are often expensive and inconvenient. SleepNet addresses these issues by introducing a new multimodal approach tailored for precise sleep apnea detection. At its core, the framework utilizes a fusion of one-dimensional convolutional neural networks (1D-CNN) and bidirectional gated recurrent units (Bi-GRU) to analyze single-lead electrocardiogram (ECG) recordings, yielding an accuracy of 95.08%. When the model is enriched with additional physiological signals-namely nasal airflow and abdominal respiratory effort-the performance further rises modestly to 95.19%. This multimodal strategy surpasses the performance of existing unimodal approaches, yielding enhanced sensitivity and specificity rates of 96.12% and 93.45%, respectively. When compared to previous studies, SleepNet represents a substantial leap forward in diagnostic efficacy, showcasing the transformative potential of integrating multiple data streams for sleep apnea detection. The results highlight the promise of deep learning methodologies in advancing this domain and lay a robust foundation for subsequent research.

摘要

睡眠呼吸暂停是一种常见的呼吸系统疾病,如果不加以治疗,会带来重大健康风险,包括心血管并发症和行为问题。传统的诊断方法,如意多导睡眠监测,虽然有效,但往往昂贵且不便。SleepNet通过引入一种专为精确检测睡眠呼吸暂停量身定制的新型多模态方法来解决这些问题。该框架的核心是利用一维卷积神经网络(1D-CNN)和双向门控循环单元(Bi-GRU)的融合来分析单导联心电图(ECG)记录,准确率达到95.08%。当模型加入额外的生理信号,即鼻气流和腹部呼吸努力时,性能进一步适度提高到95.19%。这种多模态策略超越了现有的单模态方法,灵敏度和特异度分别提高到96.12%和93.45%。与先前的研究相比,SleepNet在诊断效能上有了实质性的飞跃,展示了整合多个数据流用于睡眠呼吸暂停检测的变革潜力。研究结果凸显了深度学习方法在推动该领域发展方面的前景,并为后续研究奠定了坚实基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6d7/12394614/52a0b23e184f/41598_2025_16154_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6d7/12394614/5cf16d4f73ec/41598_2025_16154_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6d7/12394614/7597389a0f01/41598_2025_16154_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6d7/12394614/3334f7351b21/41598_2025_16154_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6d7/12394614/52a0b23e184f/41598_2025_16154_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6d7/12394614/5cf16d4f73ec/41598_2025_16154_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6d7/12394614/7597389a0f01/41598_2025_16154_Figa_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6d7/12394614/3334f7351b21/41598_2025_16154_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6d7/12394614/52a0b23e184f/41598_2025_16154_Fig3_HTML.jpg

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本文引用的文献

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Efficient Deep Learning Based Hybrid Model to Detect Obstructive Sleep Apnea.基于深度学习的高效混合模型用于阻塞性睡眠呼吸暂停检测。
Sensors (Basel). 2023 May 12;23(10):4692. doi: 10.3390/s23104692.
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基于 ECG 和 SpO2 信号的前馈人工神经网络实时睡眠呼吸暂停检测
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Contribution of Different Subbands of ECG in Sleep Apnea Detection Evaluated Using Filter Bank Decomposition and a Convolutional Neural Network.基于滤波器组分解和卷积神经网络评估 ECG 不同子带在睡眠呼吸暂停检测中的贡献。
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