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失眠的数字疗法：一项伞状综述和元元分析

Digital therapeutics for insomnia: an umbrella review and meta-meta-analysis.

作者信息

Li Can, Luo Qiyun, Wu Hong

机构信息

School of Medicine and Health Management, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

NPJ Digit Med. 2025 Aug 28;8(1):554. doi: 10.1038/s41746-025-01946-y.

DOI:10.1038/s41746-025-01946-y
PMID:40877427
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12394607/
Abstract

The growing burden of insomnia underscores the necessity for accessible and effective treatments, with digital therapeutics offering a promising solution. A systematic search was conducted across seven databases (PubMed, Web of Science, EMBASE, MEDLINE, ProQuest, Scopus, and the Cochrane Library) covering the period from the inception of each database until October 2024. A total of 28 systematic reviews and meta-analyses evaluating digital therapeutics with reported insomnia-related outcomes were included, encompassing 118,970 participants. The primary outcome, Insomnia Severity Index (ISI), indicated that digital therapeutics significantly improved insomnia (SMD = -0.42, p < 0.01), with better results observed during follow-up (SMD = -0.69, p < 0.01). Under the guidance of therapists, digital therapeutics exerted a more positive effect (SMD = -1.05, p < 0.01). The secondary outcomes also showed consistent results, with no significant differences observed in Total Sleep Time (TST) between the post-intervention and follow-up periods. Based on the assessment results, there is sufficient evidence to recommend the use of digital therapeutics.

摘要

失眠负担日益加重，凸显了获得便捷有效治疗方法的必要性，数字疗法提供了一个有前景的解决方案。我们对七个数据库（PubMed、科学网、EMBASE、MEDLINE、ProQuest、Scopus和考克兰图书馆）进行了系统检索，涵盖每个数据库创建至2024年10月的时间段。总共纳入了28项评估数字疗法与失眠相关结果的系统评价和荟萃分析，涉及118,970名参与者。主要结局指标失眠严重程度指数（ISI）表明，数字疗法显著改善了失眠（标准化均数差[SMD]= -0.42，p<0.01），随访期间效果更佳（SMD= -0.69，p<0.01）。在治疗师指导下，数字疗法发挥了更积极的效果（SMD= -1.05，p<…

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d88/12394607/369ae77f2a56/41746_2025_1946_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d88/12394607/49c3184fe93c/41746_2025_1946_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d88/12394607/83c526029aa2/41746_2025_1946_Fig2_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d88/12394607/42a033bc7743/41746_2025_1946_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d88/12394607/7ebba9d12859/41746_2025_1946_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d88/12394607/369ae77f2a56/41746_2025_1946_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d88/12394607/49c3184fe93c/41746_2025_1946_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d88/12394607/83c526029aa2/41746_2025_1946_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d88/12394607/2aa85e4617ce/41746_2025_1946_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d88/12394607/42a033bc7743/41746_2025_1946_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d88/12394607/7ebba9d12859/41746_2025_1946_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d88/12394607/369ae77f2a56/41746_2025_1946_Fig6_HTML.jpg

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