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针对癌症疼痛和癌症相关呼吸困难患者的阿片类药物引起的恶心和呕吐（OINV）的药理学止吐预防和治疗。

Pharmacological antiemetic prophylaxis and treatment for opioid-induced nausea and vomiting (OINV) in patients treated for cancer pain and cancer-related breathlessness.

作者信息

Gaertner Jan, Appenzeller-Herzog Christian, Piechotta Vanessa, Schwarzer Guido, Rémi Constanze, Suter Katja, Boehlke Christopher

机构信息

Department of Clinical Research, University Hospital and University of Basel, Basel, Switzerland.

Palliative Care Center, Bethesda Hospital, Basel, Switzerland.

出版信息

Cochrane Database Syst Rev. 2025 Aug 29;8(8):CD016207. doi: 10.1002/14651858.CD016207.

DOI:10.1002/14651858.CD016207
PMID:40878845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12395543/
Abstract

This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the benefits and harms of pharmacological treatments given prophylactically or on-demand after onset of opioid-induced nausea and vomiting (OINV) in people being treated for cancer pain or cancer dyspnoea, when compared to placebo or other pharmacological interventions.

摘要

这是一项Cochrane系统评价（干预措施）的方案。目标如下：与安慰剂或其他药物干预措施相比，评估在接受癌症疼痛或癌症呼吸困难治疗的患者中，预防性或在阿片类药物引起的恶心和呕吐（OINV）发作后按需给予药物治疗的益处和危害。

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本文引用的文献

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Cochrane Database Syst Rev. 2024 Sep 12;9(9):CD015383. doi: 10.1002/14651858.CD015383.pub2.
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Pharmacological treatment of cancer pain and opioid induced nausea and vomiting: online survey and comparison with current guidelines.癌症疼痛和阿片类药物引起的恶心呕吐的药物治疗：在线调查及与现行指南的比较。
Support Care Cancer. 2024 Jun 15;32(7):436. doi: 10.1007/s00520-024-08628-7.
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Guidance on terminology, application, and reporting of citation searching: the TARCiS statement.引文检索的术语、应用及报告指南：TARCiS声明
BMJ. 2024 May 9;385:e078384. doi: 10.1136/bmj-2023-078384.
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The Automated Systematic Search Deduplicator (ASySD): a rapid, open-source, interoperable tool to remove duplicate citations in biomedical systematic reviews.自动化系统搜索去重器 (ASySD)：一种快速、开源、可互操作的工具，用于去除生物医学系统评价中的重复引文。
BMC Biol. 2023 Sep 7;21(1):189. doi: 10.1186/s12915-023-01686-z.
5
A structured approach to information retrieval improved identification of funding and researchers' conflicts of interest in trials included in Cochrane reviews.一种结构化的信息检索方法提高了 Cochrane 综述中试验的资金和研究人员利益冲突的识别能力。
J Clin Epidemiol. 2023 Sep;161:104-115. doi: 10.1016/j.jclinepi.2023.06.020. Epub 2023 Jul 1.
6
Update on Prevalence of Pain in Patients with Cancer 2022: A Systematic Literature Review and Meta-Analysis.《2022年癌症患者疼痛患病率最新情况：系统文献综述与荟萃分析》
Cancers (Basel). 2023 Jan 18;15(3):591. doi: 10.3390/cancers15030591.
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Use of Opioids for Adults With Pain From Cancer or Cancer Treatment: ASCO Guideline.阿片类药物在患有癌症疼痛或癌症治疗疼痛的成人中的应用：美国临床肿瘤学会指南。
J Clin Oncol. 2023 Feb 1;41(4):914-930. doi: 10.1200/JCO.22.02198. Epub 2022 Dec 5.
8
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