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Potential Protective Role of Galectin-3 in Airway Dilatation in Obstructive Airway Diseases.

作者信息

Kogo Mariko, Matsumoto Hisako, Tanabe Naoya, Morimoto Chie, Nomura Natsuko, Sunadome Hironobu, Nagasaki Tadao, Sato Susumu, Sato Atsuyasu, Oguma Tsuyoshi, Ito Isao, Hirai Toyohiro

机构信息

Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Department of Respiratory Medicine and Allergology, Kindai University Faculty of Medicine, Osaka, Japan.

出版信息

Clin Transl Allergy. 2025 Aug;15(8):e70092. doi: 10.1002/clt2.70092.

DOI:10.1002/clt2.70092
PMID:40879145
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12328036/
Abstract
摘要

相似文献

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Galectin-3 disrupts tight junctions of airway epithelial cell monolayers by inducing expression and release of matrix metalloproteinases upon influenza A infection.半乳糖凝集素-3通过在甲型流感病毒感染时诱导基质金属蛋白酶的表达和释放来破坏气道上皮细胞单层的紧密连接。
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本文引用的文献

1
Exploring the roles of airway dipeptidyl peptidase 1 in obstructive airway disease.探索气道二肽基肽酶1在阻塞性气道疾病中的作用。
ERJ Open Res. 2025 May 19;11(3). doi: 10.1183/23120541.00841-2024. eCollection 2025 May.
2
Emerging Roles of Galectin-3 in Pulmonary Diseases.Galectin-3 在肺部疾病中的新兴作用。
Lung. 2024 Aug;202(4):385-403. doi: 10.1007/s00408-024-00709-y. Epub 2024 Jun 8.
3
Bronchiectasis in severe asthma and asthmatic components in bronchiectasis.严重哮喘中的支气管扩张症和支气管扩张症中的哮喘成分。
Respir Investig. 2022 Mar;60(2):187-196. doi: 10.1016/j.resinv.2021.11.004. Epub 2021 Dec 16.
4
Bronchiectasis Rheumatoid Overlap Syndrome Is an Independent Risk Factor for Mortality in Patients With Bronchiectasis: A Multicenter Cohort Study.支气管扩张症-类风湿关节炎重叠综合征是支气管扩张症患者死亡的独立危险因素：一项多中心队列研究
Chest. 2017 Jun;151(6):1247-1254. doi: 10.1016/j.chest.2016.12.024. Epub 2017 Jan 16.
5
Anti-inflammatory deficiencies in neutrophilic asthma: reduced galectin-3 and IL-1RA/IL-1β.嗜中性粒细胞性哮喘中的抗炎缺陷：半乳糖凝集素-3和白细胞介素-1受体拮抗剂/白细胞介素-1β降低
Respir Res. 2015 Jan 24;16(1):5. doi: 10.1186/s12931-014-0163-5.
6
Reference values for spirometry, including vital capacity, in Japanese adults calculated with the LMS method and compared with previous values.采用LMS法计算日本成年人肺活量等肺量计参考值，并与先前的值进行比较。
Respir Investig. 2014 Jul;52(4):242-50. doi: 10.1016/j.resinv.2014.03.003. Epub 2014 May 6.
7
Lectins offer new perspectives in the development of macrophage-targeted therapies for COPD/emphysema.凝集素为 COPD/肺气肿的巨噬细胞靶向治疗的发展提供了新的视角。
PLoS One. 2013;8(2):e56147. doi: 10.1371/journal.pone.0056147. Epub 2013 Feb 18.
8
Galectin-3 functions as an adhesion molecule to support eosinophil rolling and adhesion under conditions of flow.半乳糖凝集素-3作为一种黏附分子，在流动条件下支持嗜酸性粒细胞滚动和黏附。
J Immunol. 2007 Dec 1;179(11):7800-7. doi: 10.4049/jimmunol.179.11.7800.
9
Elastase-mediated phosphatidylserine receptor cleavage impairs apoptotic cell clearance in cystic fibrosis and bronchiectasis.弹性蛋白酶介导的磷脂酰丝氨酸受体裂解损害囊性纤维化和支气管扩张症中凋亡细胞的清除。
J Clin Invest. 2002 Mar;109(5):661-70. doi: 10.1172/JCI13572.