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稳定性心绞痛的检测。专家意见与决策分析。

Testing stable angina. Expert opinion versus decision analysis.

作者信息

Manu P, Runge L A

出版信息

Med Care. 1985 Dec;23(12):1381-90.

PMID:4087952
Abstract

Controversy still surrounds the use of invasive and noninvasive tests after establishing the clinical diagnosis of stable angina pectoris. The authors employed threshold analysis, a multifactorial mathematical instrument, and the risk and benefit data available in 1983 to determine that the optimal diagnostic approach is to perform a stress test first and then consider angiographic evaluation and surgery for those patients with a positive result. This decision rule was compared with the diagnostic approaches proposed by 61 randomly selected board-certified cardiologists. Fifteen different two-test strategies were proposed by the 61 experts. Fifty-three chose a stress test as the initial procedure and 37 would proceed to coronary angiography if the stress test were positive. Thus a majority of the experts studied (60.6%) proposed an approach identical to the result of threshold analysis. Three respondents thought that no tests were necessary for the evaluation of stable angina pectoris. Twelve cardiologists would not recommend coronary angiography in stable angina patients with unequivocally positive stress tests. Their degree of familiarity and practical experience with the invasive procedure, as well as their perception of risks and benefits of coronary angiography and coronary artery bypass surgery, was not different than that of the cardiologists holding the majority view. For this group the decision analytic model could be used to correct judgmental biases and to optimize the diagnostic evaluation of coronary artery disease.

摘要

在确立稳定型心绞痛的临床诊断后,侵入性和非侵入性检查的应用仍然存在争议。作者采用阈值分析(一种多因素数学工具)以及1983年可得的风险和获益数据,以确定最佳诊断方法是先进行负荷试验,然后对结果呈阳性的患者考虑进行血管造影评估和手术。将这一决策规则与61名随机挑选的具有委员会认证的心脏病专家提出的诊断方法进行了比较。这61位专家提出了15种不同的两步检查策略。53人选择负荷试验作为初始检查,37人会在负荷试验呈阳性时接着进行冠状动脉造影。因此,大多数接受研究的专家(60.6%)提出了与阈值分析结果相同的方法。3名受访者认为评估稳定型心绞痛无需进行检查。12名心脏病专家不会建议对负荷试验明确呈阳性的稳定型心绞痛患者进行冠状动脉造影。他们对侵入性操作的熟悉程度和实践经验,以及他们对冠状动脉造影和冠状动脉旁路移植术的风险和获益的认知,与持多数观点的心脏病专家并无不同。对于这一组人,决策分析模型可用于纠正判断偏差并优化冠心病的诊断评估。

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