Castagneto-Gissey Lidia, Russo Maria Francesca, Palumbo Piergaspare, Casella-Mariolo James, D'Andrea Vito, Bellini Maria Irene, Illuminati Giulio, Casella Giovanni
Department of Surgery, Sapienza University of Rome, Viale Regina Elena, 324, Rome, 00161, Italy.
Department of General and Emergency Surgery, Ospedale dei Castelli (NOC), ASL Roma 6, Rome, Italy.
Hernia. 2025 Aug 29;29(1):264. doi: 10.1007/s10029-025-03430-8.
This systematic review and meta-analysis aims to evaluate the outcomes of laparoendoscopic extraperitoneal techniques for repairing rectus diastasis (RD) with concomitant ventral hernias, focusing on recurrence rates, surgical site occurrences, and the effectiveness of various surgical approaches and mesh placement sites.
A comprehensive literature search was conducted using PubMed and the Cochrane Library, adhering to PRISMA guidelines. Prospective and retrospective cohort studies involving adults with RD and concomitant ventral hernias were included. Surgical techniques were classified based on working space (subcutaneous vs. retromuscular) and wall repair technique (stapled vs. fascial plication suture). The primary outcome was recurrence of RD or hernia, and secondary outcomes included seroma, surgical site infections (SSIs), and bleeding.
Twenty-two studies comprising 1,616 patients were analyzed. Mean age was 45.6 years, BMI 30.5 kg/m², with a mean follow-up of 10.5 months. All studies were non-randomized and rated as having a "Serious" risk of bias using the ROBINS-I tool. Recurrence occurred in 19 patients (0.99%), with no significant differences between subcutaneous and retromuscular approaches (0.93% vs. 1.16%, p = 0.802) or between stapled and fascial plication techniques (0% vs. 1.18%, p = 0.090). Seroma rates were significantly higher in the subcutaneous group compared to retromuscular approach (11.8% vs. 0.70%, p < 0.001). SSIs were more common in subcutaneous approaches (2.33% vs. 0.58%, 0.005). Bleeding was low across all groups (1.3%), with higher rates in the stapled compared to the fascial plication group (6.39% vs. 0.37%, p < 0.001).
Laparoendoscopic extraperitoneal approaches for RD and ventral hernia repair demonstrate favorable outcomes, with low and comparable recurrence rates among subgroups. The subcutaneous approach is associated with a higher risk of seroma formation while the stapled technique may increase bleeding risk. Further studies with higher methodological quality are needed to guide optimal technique selection.
本系统评价和荟萃分析旨在评估腹腔镜腹膜外技术修复伴有腹直肌分离(RD)的腹疝的效果,重点关注复发率、手术部位并发症以及各种手术方法和补片放置部位的有效性。
按照PRISMA指南,使用PubMed和Cochrane图书馆进行全面的文献检索。纳入涉及患有RD和伴有腹疝的成年人的前瞻性和回顾性队列研究。手术技术根据工作空间(皮下与肌后)和腹壁修复技术(吻合器与筋膜折叠缝合)进行分类。主要结局是RD或疝的复发,次要结局包括血清肿、手术部位感染(SSI)和出血。
分析了22项研究,共1616例患者。平均年龄为45.6岁,体重指数为30.5kg/m²,平均随访10.5个月。所有研究均为非随机研究,使用ROBINS-I工具评估为具有“严重”偏倚风险。19例患者(0.99%)出现复发,皮下和肌后手术方法之间(0.93%对1.16%,p=0.802)或吻合器与筋膜折叠技术之间(0%对1.18%,p=0.090)无显著差异。皮下组血清肿发生率显著高于肌后手术方法(11.8%对0.70%,p<0.001)。SSI在皮下手术方法中更常见(2.33%对0.58%,p=0.005)。所有组出血率均较低(1.3%),吻合器组出血率高于筋膜折叠组(6.39%对0.37%,p<0.001)。
腹腔镜腹膜外方法修复RD和腹疝显示出良好的效果,亚组间复发率低且相当。皮下手术方法血清肿形成风险较高,而吻合器技术可能增加出血风险。需要更高方法学质量的进一步研究来指导最佳技术选择。