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[豚鼠(Cavia porcellus)复合动作电位长期记录的植入技术。方法比较]

[Implantation technics for long-term recording of the compound action potentials in the guinea pig, Cavia porcellus. A comparison of methods].

作者信息

Walger M, Schmidt U, von Wedel H

出版信息

Laryngol Rhinol Otol (Stuttg). 1985 Dec;64(12):638-41.

PMID:4087996
Abstract

Long-term recordings of the compound action potential of the acoustic nerve of young, pigmented guinea pigs were carried out by two different techniques of implantation. The electrodes were inserted either by way of the mastoid process into the bony recess above the round window or they were introduced into the facial canal via the stylomastoid foramen. Before and after each implantation, special tests (Preyer-reflex, otoscopy, impedance audiometry) were performed for preliminary selection of the animals and to discover postoperative induced disturbances of sound conduction in the middle ear. These tests showed that the proportion of operatively induced middle ear inflammations was reduced from 24 to 10%, if electrodes were implanted into the facial canal.

摘要

采用两种不同的植入技术,对幼年有色豚鼠听神经复合动作电位进行了长期记录。电极要么经乳突进入圆窗上方的骨隐窝,要么经茎乳孔进入面神经管。每次植入前后,都进行了特殊测试(普赖尔反射、耳镜检查、声阻抗测听),以便对动物进行初步筛选,并发现术后中耳传音诱发的障碍。这些测试表明,如果将电极植入面神经管,手术诱发的中耳炎症比例从24%降至10%。

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