HCAR2 the rescue: sensing heme, steering inflammation.
作者信息
Liu Yunfeng, Yazdanbakhsh Karina
机构信息
Laboratory of Complement Biology, New York Blood Center, New York, NY.
出版信息
Blood Adv. 2025 Sep 9;9(17):4486-4487. doi: 10.1182/bloodadvances.2025016946.
Abstract
摘要
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本文引用的文献
1
HCAR2 is a novel receptor for heme.HCAR2是一种新型的血红素受体。
Blood Adv. 2025 Sep 9;9(17):4458-4469. doi: 10.1182/bloodadvances.2025016197.
2
Role of Toll-like receptor 4 in intravascular hemolysis-mediated injury.Toll 样受体 4 在血管内溶血介导损伤中的作用。
J Pathol. 2022 Nov;258(3):236-249. doi: 10.1002/path.5995. Epub 2022 Aug 26.
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Murine bone marrow mesenchymal stromal cells have reduced hematopoietic maintenance ability in sickle cell disease.鼠骨髓间充质基质细胞在镰状细胞病中造血维持能力降低。
Blood. 2021 Dec 16;138(24):2570-2582. doi: 10.1182/blood.2021012663.
4
Regulation of inflammation by the antioxidant haem oxygenase 1.抗氧化血红素加氧酶 1 对炎症的调节。
Nat Rev Immunol. 2021 Jul;21(7):411-425. doi: 10.1038/s41577-020-00491-x. Epub 2021 Jan 29.
5
Intravascular hemolysis and the pathophysiology of sickle cell disease.血管内溶血与镰状细胞病的病理生理学
J Clin Invest. 2017 Mar 1;127(3):750-760. doi: 10.1172/JCI89741.
6
Anti-inflammatory effects of the hydroxycarboxylic acid receptor 2.羟基羧酸受体2的抗炎作用
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Effect of extended-release niacin on serum lipids and on endothelial function in adults with sickle cell anemia and low high-density lipoprotein cholesterol levels.缓释烟酸对伴有低高密度脂蛋白胆固醇水平的镰状细胞贫血成年患者血脂和内皮功能的影响。
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Characterization of heme as activator of Toll-like receptor 4.血红素作为Toll样受体4激活剂的特性研究
J Biol Chem. 2007 Jul 13;282(28):20221-9. doi: 10.1074/jbc.M610737200. Epub 2007 May 14.
9
Neutrophil activation by heme: implications for inflammatory processes.血红素介导的中性粒细胞活化：对炎症过程的影响
Blood. 2002 Jun 1;99(11):4160-5. doi: 10.1182/blood.v99.11.4160.
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