Fabritius H, Sangare A, Kple-Faget P, Cabannes R
Med Trop (Mars). 1985 Oct-Dec;45(4):423-7.
Detection of 11 cases of hemoglobin "Hope" after family study in three isolated cases led us to establish an hematologic profile of this hemoglobin. The first observation which can be done is the geographic origin of the propositus. All of these originated from the sub-sahelian zone. The second observation is the discovery of anemia for all carriers of this hemoglobin.
在对3例孤立病例进行家系研究后检测到11例血红蛋白“Hope”,这使我们得以建立这种血红蛋白的血液学特征。首先可以进行的观察是先证者的地理来源。所有这些先证者都来自萨赫勒以南地区。第二个观察结果是发现所有携带这种血红蛋白的人都患有贫血。