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Atypical presentation of a large posterior falx meningioma involving the parafalcine region in a 78-year-female: A case report.

作者信息

AlSabea Nadeem, Syeda Samar, Gubran Marina, Gibatova Viktoriya, Sharma Rahul, Aswani Anjiya

机构信息

Department of Internal Medicine, Mount Sinai Hospital, Chicago, IL 60608, United States.

Department of Internal Medicine, Ross University, Chicago, IL 60608, United States.

出版信息

World J Clin Cases. 2025 Sep 6;13(25):108429. doi: 10.12998/wjcc.v13.i25.108429.


DOI:10.12998/wjcc.v13.i25.108429
PMID:40881232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12243921/
Abstract

BACKGROUND: Meningiomas represent the most common primary intracranial tumor in adults. The majority of meningiomas are indolent, benign, and sporadic in nature. The incidence of meningiomas is directly proportional to the age, peaking around 65 years. The presenting symptomatology of intracranial meningiomas is mainly dependent on their anatomical location, as with the majority of brain tumors. Surgical resection and radiation therapy remain the treatment modality for meningiomas of all grades. CASE SUMMARY: We present a case describing a 78-year-old female who came in following a ground level fall. The primary assessment was notable for a history of similar recurrent falls and subtle left-sided peripheral visual field loss. Further neurological examination was otherwise largely unremarkable. A computed tomography scan of the head revealed a large extra-axial mass located along the posterior aspect of the falx. Follow-up magnetic resonance imaging confirmed a lesion measuring around 6.6 cm × 4.2 cm × 5.5 cm. A partial surgical resection of the right-sided portion of the lesion was performed. Complete resection was limited by insufficient visualization and challenges with hemostatic control of the left parafalcine region. Further histopathological analysis confirmed a fibrous meningioma with focal necrosis, consistent with World Health Organization Grade 2 classification. She was subsequently scheduled for outpatient follow-up to assess the residual tumor management. CONCLUSION: This case highlights the importance of maintaining a high index of suspicion for intracranial pathology in elderly patients with nonspecific presentation.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46cc/12243921/f550ce3c3729/wjcc-13-25-108429-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46cc/12243921/976aabb39a43/wjcc-13-25-108429-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46cc/12243921/8f4a482db306/wjcc-13-25-108429-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46cc/12243921/f550ce3c3729/wjcc-13-25-108429-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46cc/12243921/976aabb39a43/wjcc-13-25-108429-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46cc/12243921/8f4a482db306/wjcc-13-25-108429-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46cc/12243921/f550ce3c3729/wjcc-13-25-108429-g003.jpg

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本文引用的文献

[1]
CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2017-2021.

Neuro Oncol. 2024-10-6

[2]
CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2015-2019.

Neuro Oncol. 2022-10-5

[3]
An overview of meningiomas.

Future Oncol. 2018-8-7

[4]
The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.

Acta Neuropathol. 2016-5-9

[5]
Histological-subtypes and anatomical location correlated in meningeal brain tumors (meningiomas).

J Neurosci Rural Pract. 2014-7

[6]
The histopathological spectrum of human meningiomas.

Int J Clin Exp Pathol. 2012

[7]
Newly codified glial neoplasms of the 2007 WHO Classification of Tumours of the Central Nervous System: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma.

Brain Pathol. 2007-7

[8]
Solitary fibrous tumor of the meninges: a lesion distinct from fibrous meningioma. A clinicopathologic and immunohistochemical study.

Am J Clin Pathol. 1996-8

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