BACKGROUND

Conjunctival plasmacytoma is an exceedingly uncommon form of extramedullary manifestation of multiple myeloma, with only a handful of cases reported so far.

CASE SUMMARY

A 66-year-old male of Indian origin with multiple myeloma presented with a 1-year history of progressive pink mass associated with itching in his left eye. Examination revealed a pinkish conjunctival mass with telangiectasia extending up to the temporal limbus, mimicking ocular surface squamous neoplasia. The patient underwent successful excision of the mass and amniotic membrane grafting. Histopathological examination after excision revealed plasma cell infiltration, confirming an unusual extramedullary manifestation of multiple myeloma. The patient was followed up for one year, with no evidence of recurrence.

CONCLUSION

This case report highlights the importance of considering multiple myeloma in the differential diagnosis of ocular masses, particularly in patients with a known history of the disease. The presentation of a conjunctival mass in a patient with multiple myeloma is rare, but it is essential to recognize this possibility to ensure timely and appropriate management.