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[儿童特发性慢性便秘伴巨直肠的病理生理学与治疗]

[Pathophysiology and treatment of idiopathic chronic constipation with megarectum in children].

作者信息

Amano S, Tsukamoto Y, Sakurai A, Funada M, Koike H, Honzumi M, Suzuki H

出版信息

Nihon Geka Gakkai Zasshi. 1985 Sep;86(9):1273-6.

PMID:4088252
Abstract

Anorectal manometry was carried out in 65 children with idiopathic chronic constipation. Forty-five had no megarectum, and 20 had megarectum. Patients without megarectum showed normal anorectal pressures, recto-anal reflex, rectal sensation and rectal compliance, but motility of the colon was disturbed in these patients. Patients with megarectum also had normal anorectal pressures, recto-anal reflex and rectal sensation, but they showed remarkably high rectal compliance, or excessive rectal reservoir. Patients without megarectum were treated with laxatives and all of them were cured within 6 months after institution of therapy. Patients with megarectum were treated with rectal washout and suppository and 14 out of 20 were cured within 10 months. Six out of 20 patients with megarectum, however, were resistant to conservative therapy and necessity of surgical treatment to reduce the excessive rectal reservoir was proposed for these patients.

摘要

对65例特发性慢性便秘患儿进行了肛门直肠测压。其中45例无巨直肠,20例有巨直肠。无巨直肠的患者肛门直肠压力、直肠肛门反射、直肠感觉和直肠顺应性均正常,但这些患者的结肠动力受到干扰。有巨直肠的患者肛门直肠压力、直肠肛门反射和直肠感觉也正常,但他们的直肠顺应性显著升高,即直肠储器过大。无巨直肠的患者用泻药治疗,所有患者在治疗开始后6个月内治愈。有巨直肠的患者采用直肠冲洗和栓剂治疗,20例中有14例在10个月内治愈。然而,20例有巨直肠的患者中有6例对保守治疗耐药,建议对这些患者进行手术治疗以减少过大的直肠储器。

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