Dysregulation of hsa-mir-10a-5p modulates RNF186 and contributes to ulcerative colitis pathogenesis.

作者信息

Guo Yifan, Wu Haidong, Wang Liudan, Miao Xinpu

机构信息

Department of Gastroenterology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, #19, Xiuhua Road, Xiuying District, Haikou, 570311, Hainan, China.

出版信息

Mol Biol Rep. 2025 Aug 30;52(1):857. doi: 10.1007/s11033-025-10939-9.

DOI:10.1007/s11033-025-10939-9

PMID:40884729

Abstract

摘要

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本文引用的文献

[1]

Exploring the mechanism of the Fructus Mume and Rhizoma Coptidis herb pair intervention in Ulcerative Colitis from the perspective of inflammation and immunity based on systemic pharmacology.

BMC Complement Med Ther. 2023-1-16

[2]

PPARGC1A affects inflammatory responses in photodynamic therapy (PDT)-treated inflammatory bowel disease (IBD).

Biochem Pharmacol. 2022-8

[3]

Identification of Immune-Related Gene Signature and Prediction of CeRNA Network in Active Ulcerative Colitis.

Front Immunol. 2022

[4]

The Impact of MicroRNAs during Inflammatory Bowel Disease: Effects on the Mucus Layer and Intercellular Junctions for Gut Permeability.

Cells. 2021-11-30

[5]

RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis.

Autophagy. 2021-10

[6]

Role and mechanisms of exosomal miRNAs in IBD pathophysiology.

Am J Physiol Gastrointest Liver Physiol. 2020-12-1

[7]

MicroRNAs Regulate Intestinal Immunity and Gut Microbiota for Gastrointestinal Health: A Comprehensive Review.

Genes (Basel). 2020-9-12

[8]

Hsa-miR-10a-5p promotes pancreatic cancer growth by BDNF/SEMA4C pathway.

J Biol Regul Homeost Agents. 2020

[9]

Alteration of miR-21, miR-433 and miR-590 tissue expression related to the TGF-β signaling pathway in ulcerative colitis patients.

Arch Physiol Biochem. 2022-10

[10]

Gut Bacterial Metabolite Urolithin A (UA) Mitigates Ca Entry in T Cells by Regulating miR-10a-5p.

Front Immunol. 2019-7-31

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Dysregulation of hsa-mir-10a-5p modulates RNF186 and contributes to ulcerative colitis pathogenesis.

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