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兔实验性贝斯诺球虫感染的化学疗法

Chemotherapy of experimental Besnoitia besnoiti infection in rabbits.

作者信息

Shkap V, De Waal D T, Potgieter F T

出版信息

Onderstepoort J Vet Res. 1985 Dec;52(4):289.

PMID:4088644
Abstract

Rabbits were infected with a bovine strain of Besnoitia besnoiti parasites derived from VERO cell cultures. Oxytetracycline, given at 30 mg/kg i.m. simultaneously with infection, prevented the development of orchitis. The controls received no treatment. All infected animals showed a transient febrile reaction. It is concluded that oxytetracycline has some therapeutic potential against Besnoitia besnoiti and that rabbits are suitable models for therapeutic trials.

摘要

兔子被源自VERO细胞培养物的牛种贝氏贝诺孢子虫寄生虫感染。感染时同时肌肉注射30毫克/千克的土霉素,可预防睾丸炎的发生。对照组未接受治疗。所有受感染的动物都出现了短暂的发热反应。得出的结论是,土霉素对贝氏贝诺孢子虫有一定的治疗潜力,并且兔子是治疗试验的合适模型。

相似文献

1
Chemotherapy of experimental Besnoitia besnoiti infection in rabbits.兔实验性贝斯诺球虫感染的化学疗法
Onderstepoort J Vet Res. 1985 Dec;52(4):289.
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The artificial transmission of Besnoitia besnoiti (Marotel, 1912) from chronically infected to susceptible cattle and rabbits.贝氏贝斯诺虫(Marotel,1912年)从慢性感染牛和兔向易感牛和兔的人工传播。
Onderstepoort J Vet Res. 1967 Dec;34(2):303-16.
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Besnoitia besnoiti: chemotherapeutic trials in vivo and in vitro.贝斯诺伊球虫:体内和体外化疗试验
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Immunization against bovine besnoitiosis with a live vaccine prepared from a blue wildebeest strain of Besnoitia besnoiti grown in cell cultures. 1. Studies on rabbits.用在细胞培养物中培养的贝氏贝诺孢子虫蓝角马菌株制备的活疫苗对牛贝诺孢子虫病进行免疫接种。1. 对兔子的研究。
Onderstepoort J Vet Res. 1974 Mar;41(1):1-5.
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Vet Parasitol. 1987 Feb;23(3-4):169-78. doi: 10.1016/0304-4017(87)90002-1.
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[Studies on the therapeutic and preventive effect of orally administered tetracycline againist Aegptianella pullorum Carpano, 1928, in hen fowl].[口服四环素对1928年卡尔帕诺发现的鸡埃及小杆菌在母鸡中的治疗和预防作用的研究]
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