一种新型长效肼屈嗪类血管扩张剂ISF 2469与β受体阻滞剂及利尿剂联合使用的降压疗效。 - Suppr

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超能文献

Antihypertensive efficacy of a new long acting hydralazine like vasodilator, ISF 2469 in combination with a betablocker and a diuretic.

作者信息

van Brummelen P, Bühler F R, Kiowski W, Bolli P, Bertel O

出版信息

Int J Clin Pharmacol Biopharm. 1979 Oct;17(10):380-5.

PMID:40887

Abstract

摘要

相似文献

Antihypertensive efficacy of a new long acting hydralazine like vasodilator, ISF 2469 in combination with a betablocker and a diuretic.一种新型长效肼屈嗪类血管扩张剂ISF 2469与β受体阻滞剂及利尿剂联合使用的降压疗效。

Int J Clin Pharmacol Biopharm. 1979 Oct;17(10):380-5.

[Treatment of severe arterial hypertension with propyldazine (ISF 2123) associated with a diuretic and a beta-blocking agent].用丙酰肼（ISF 2123）联合利尿剂和β受体阻滞剂治疗重度动脉高血压

Minerva Cardioangiol. 1979 Mar;27(3):113-8.

Cadralazine, a new vasodilator, in addition to a beta-blocker for long-term treatment of hypertension.卡屈嗪，一种新型血管扩张剂，与β受体阻滞剂联合用于高血压的长期治疗。

Arzneimittelforschung. 1985;35(3):623-5.

[Beta blockaders in the treatment of hypertension. Part 2. Antihypertensive effect: hypotheses on the mechanism of action and practical methods of treatment].[β受体阻滞剂治疗高血压。第2部分。降压效果：作用机制假说及实际治疗方法]

Coeur Med Interne. 1978 Jul-Sep;17(3):381-400.

Therapy with hydrazinopyridazine, a new antihypertensive vasodilatory agent, in combination with beta-receptor blocking substances.用新型抗高血压血管扩张剂肼屈嗪与β受体阻滞剂联合进行治疗。

Int J Clin Pharmacol Ther Toxicol. 1980;18(5):233-5.

Pharmacological basis for combination therapy of hypertension.高血压联合治疗的药理学基础。

Annu Rev Pharmacol Toxicol. 1977;17:311-23. doi: 10.1146/annurev.pa.17.040177.001523.

A preliminary clinical trial of Prazosin: a new oral antihypertensive agent.哌唑嗪初步临床试验：一种新型口服抗高血压药物。

N Z Med J. 1974 May 22;79(516):969-72.

Beta-adrenoceptor blockade and vasodilatation in essential hypertension. Hemodynamic studies at rest and during exposure to stress.原发性高血压中的β-肾上腺素能受体阻滞与血管舒张。静息及应激状态下的血流动力学研究。

Acta Med Scand Suppl. 1984;689:1-46.

Current trends in the management of hypertension.高血压管理的当前趋势

Compr Ther. 1980 Mar;6(3):23-28.

Hypertension in the elderly: treatment.老年人高血压：治疗

Cardiol Clin. 1986 May;4(2):245-52.

引用本文的文献

Studies on the metabolism of cadralazine in rat.

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[14C]cadralazine: absorption, distribution and excretion in rat and dog.

Eur J Drug Metab Pharmacokinet. 1983;8(1):25-33. doi: 10.1007/BF03189578.

Cadralazine (ISF 2469): dose-related antihypertensive activity after single oral administration to patients.

Eur J Clin Pharmacol. 1983;24(2):157-61. doi: 10.1007/BF00613810.

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Eur J Drug Metab Pharmacokinet. 1985 Jul-Sep;10(3):217-23. doi: 10.1007/BF03189745.

Disposition and pharmacokinetics of cadralazine and individual metabolites in man.

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Cadralazine and chlorthalidone as a second-step drug with atenolol in hypertensive patients: differences in blood pressure control during exercise.

Eur J Clin Pharmacol. 1986;30(2):145-50. doi: 10.1007/BF00614292.

Acute systemic and renal haemodynamic effects and long-term antihypertensive action of cadralazine in patients pretreated with beta-blockers and diuretics.

Eur J Clin Pharmacol. 1987;31(5):513-8. doi: 10.1007/BF00606622.

Cadralazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the treatment of hypertension.

Drugs. 1990 Oct;40(4):543-60. doi: 10.2165/00003495-199040040-00005.

Cadralazine versus prazosin as second-step treatment in hypertensive patients on beta-blockers: a randomized multicentre study. The Italian Multicentre Study Group.

Eur J Clin Pharmacol. 1991;40(5):461-5. doi: 10.1007/BF00315223.

Pharmacokinetics of cadralazine and its hydrazino-metabolite in patients with renal impairment after repeated administration of 5 mg once daily.

Eur J Drug Metab Pharmacokinet. 1992 Jul-Sep;17(3):213-20. doi: 10.1007/BF03190148.

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