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基于远程动态监测技术的心力衰竭预警研究进展

[Research progress on the early warning of heart failure based on remote dynamic monitoring technology].

作者信息

Shi Ying, Li Mengwei, Li Lixuan, Yan Wei, Cao Desen, Zhang Zhengbo, Yan Muyang

机构信息

Chinese PLA Medical School, Beijing 100853, P. R. China.

Center for Artificial Intelligence, Chinese PLA General Hospital, Beijing 100853, P. R. China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2025 Aug 25;42(4):857-862. doi: 10.7507/1001-5515.202406007.

DOI:10.7507/1001-5515.202406007
PMID:40887203
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12409507/
Abstract

Heart failure (HF) is the end-stage of all cardiac diseases, characterized by high prevalence, high mortality, and heavy social and economic burden. Early warning of HF exacerbation is of great value for outpatient management and reducing readmission rates. Currently, remote dynamic monitoring technology, which captures changes in hemodynamic and physiological parameters of HF patients, has become the primary method for early warning and is a hot research topic in clinical studies. This paper systematically reviews the progress in this field, which was categorized into invasive monitoring based on implanted devices, non-invasive monitoring based on wearable devices, and other monitoring technologies based on audio and video. Invasive monitoring primarily involves direct hemodynamic parameters such as left atrial pressure and pulmonary artery pressure, while non-invasive monitoring covers parameters such as thoracic impedance, electrocardiogram, respiration, and activity levels. These parameters exhibit characteristic changes in the early stages of HF exacerbation. Given the clinical heterogeneity of HF patients, multi-source information fusion analysis can significantly improve the prediction accuracy of early warning models. The results of this study suggest that, compared with invasive monitoring, non-invasive monitoring technology, with its advantages of good patient compliance, ease of operation, and cost-effectiveness, combined with AI-driven multimodal data analysis methods, shows significant clinical application potential in establishing an outpatient management system for HF.

摘要

心力衰竭(HF)是所有心脏疾病的终末期,具有高患病率、高死亡率以及沉重的社会和经济负担的特点。HF病情恶化的早期预警对于门诊管理和降低再入院率具有重要价值。目前,能够捕捉HF患者血液动力学和生理参数变化的远程动态监测技术已成为早期预警的主要方法,也是临床研究中的一个热门研究课题。本文系统回顾了该领域的进展,其被分为基于植入设备的侵入性监测、基于可穿戴设备的非侵入性监测以及基于音频和视频的其他监测技术。侵入性监测主要涉及诸如左心房压力和肺动脉压力等直接血液动力学参数,而非侵入性监测涵盖胸阻抗、心电图、呼吸和活动水平等参数。这些参数在HF病情恶化的早期阶段呈现出特征性变化。鉴于HF患者的临床异质性,多源信息融合分析可显著提高预警模型的预测准确性。本研究结果表明,与侵入性监测相比,非侵入性监测技术具有患者依从性好、操作简便和性价比高的优势,结合人工智能驱动的多模态数据分析方法,在建立HF门诊管理系统方面显示出显著的临床应用潜力。

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本文引用的文献

1
Cost-effectiveness of remote haemodynamic monitoring by an implantable pulmonary artery pressure monitoring sensor (CardioMEMS-HF system) in chronic heart failure in the Netherlands.荷兰慢性心力衰竭患者应用植入式肺动脉压力监测传感器(CardioMEMS-HF 系统)进行远程血液动力学监测的成本效益分析。
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Heart Failure Remote Monitoring: A Review and Implementation How-To.心力衰竭远程监测:综述与实施指南
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Fewer Worsening Heart Failure Events With HeartLogic on top of Standard Care: a Propensity-Matched Cohort Analysis.标准治疗基础上加用心Logic 可减少心力衰竭恶化事件:倾向评分匹配队列分析。
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Lancet. 2023 Jun 24;401(10394):2113-2123. doi: 10.1016/S0140-6736(23)00923-6. Epub 2023 May 20.
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Safety, usability, and performance of a wireless left atrial pressure monitoring system in patients with heart failure: the VECTOR-HF trial.心力衰竭患者中无线左心房压力监测系统的安全性、可用性和性能:VECTOR-HF试验
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8
Effects of remote haemodynamic-guided heart failure management in patients with different subtypes of pulmonary hypertension: insights from the MEMS-HF study.远程血流动力学指导的心力衰竭管理对不同亚型肺动脉高压患者的影响:来自MEMS-HF研究的见解
Eur J Heart Fail. 2022 Dec;24(12):2320-2330. doi: 10.1002/ejhf.2656. Epub 2022 Nov 3.
9
Multiple cArdiac seNsors for mAnaGEment of Heart Failure (MANAGE-HF) - Phase I Evaluation of the Integration and Safety of the HeartLogic Multisensor Algorithm in Patients With Heart Failure.多心脏传感器用于心力衰竭管理(MANAGE-HF)-HeartLogic 多传感器算法在心力衰竭患者中的整合和安全性的 I 期评估。
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