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Letter to the Editor Regarding "The Safety and Efficacy of Intravenous Ibuprofen in Older Patients: A Retrospective Subgroup Analysis"-Reframing Intravenous Ibuprofen Use in Geriatric Pain Management: Insights on Safety, Stratification, and Polypharmacy.

作者信息

Rattanapitoon Schawanya K, La Nav, Pechdee Phornpitcha, Rattanapitoon Nathkapach K

机构信息

FMC Medical Center, Nakhon Ratchasima, Thailand.

Faculty of Medicine, International University, Phnom Penh, Cambodia.

出版信息

Clin Ther. 2025 Aug 30. doi: 10.1016/j.clinthera.2025.08.005.

DOI:10.1016/j.clinthera.2025.08.005
PMID:40887331
Abstract

We commend the retrospective subgroup analysis by Gan et al. for addressing a vital concern in geriatric pharmacotherapy-balancing analgesic efficacy with safety in older patients. Although their findings reinforce the utility of intravenous ibuprofen for acute postoperative pain, we offer further perspectives on patient selection, comorbid risk profiles, and polypharmacy, particularly in frail or polymorbid geriatric populations. This letter expands on practical and clinical considerations in translating these findings into real-world settings.

摘要

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