Akkar Ilyas, Ataş Abdullah Enes, Dogan Mustafa Hakan, Turgut Zeynep Iclal, Yilmaz Kars Merve, Cicek Orhan, Kizilarslanoglu Muhammet Cemal
Department of Internal Medicine and Division of Geriatrics, Hamidiye School of Medicine, Konya City Hospital, University of Health Sciences Türkiye, Konya, Türkiye.
Department of Radiology, School of Medicine, Necmettin Erbakan University, Konya, Türkiye.
Australas J Ageing. 2025 Sep;44(3):e70088. doi: 10.1111/ajag.70088.
This study examined the association between the psoas muscle index (PMI), hospital clinical outcomes and long-term survival in older patients hospitalised in a geriatric ward.
This retrospective study included 173 patients aged 65 years or older hospitalised in a geriatric ward (August 2020-December 2023). The PMI was measured via abdominal CT and calculated as the psoas muscle area divided by body surface area (mm/m). The post-discharge status of discharged patients was assessed through telephone interviews.
The median age of the patients (58%, female) was 80 years (65-112 years). The median PMI value was significantly lower in patients who died in the hospital than in those who survived (p = .01). In long-term follow-up, median PMI was significantly lower in female patients who died than in survivors (p = .02). In multiple regression analyses, PMI was shown to be independently associated with in-hospital mortality in all study populations and long-term mortality in female patients. In the whole study population, the optimal cut-off value of PMI for predicting in-hospital mortality was ≤407.3 mm/m (p = .02); for females, it was ≤406.5 mm/m (p < .001); for males, it was ≤633.9 mm/m (p = .03). In female patients, the optimal cut-off value of PMI for predicting long-term mortality was ≤406.5 mm/m (p = .02); however, for the whole population and male patients, it was not statistically significant.
This study demonstrates that low PMI might be related to increases in in-hospital and long-term mortality rates in hospitalised older individuals. The PMI measurement may be a potential marker for predicting mortality in hospitalised older patients.
本研究探讨老年病房住院老年患者的腰大肌指数（PMI）与医院临床结局及长期生存之间的关联。
这项回顾性研究纳入了173名年龄在65岁及以上、于老年病房住院的患者（2020年8月至2023年12月）。通过腹部CT测量PMI，并计算为腰大肌面积除以体表面积（mm/m）。通过电话访谈评估出院患者的出院后状况。
患者的中位年龄为80岁（65 - 112岁），女性占58%。在医院死亡的患者中，PMI的中位值显著低于存活患者（p = 0.01）。在长期随访中，死亡的女性患者的中位PMI显著低于存活者（p = 0.02）。在多元回归分析中，PMI在所有研究人群中均与院内死亡率独立相关，在女性患者中与长期死亡率独立相关。在整个研究人群中，预测院内死亡率的PMI最佳截断值为≤407.3 mm/m（p = 0.02）；女性为≤406.5 mm/m（p < 0.001）；男性为≤633.9 mm/m（p = 0.03）。在女性患者中，预测长期死亡率的PMI最佳截断值为≤406.5 mm/m（p = 0.02）；然而，对于整个群体和男性患者，该值无统计学意义。
本研究表明，低PMI可能与住院老年个体的院内及长期死亡率增加有关。PMI测量可能是预测住院老年患者死亡率的一个潜在指标。
