Hedvall Hannes, Andersson Erik, Ivanov Volen Z, Bragesjö Maria
Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.
Department of Clinical Neuroscience, Division of Psychology, Karolinska Institutet, Stockholm, Sweden.
Eur J Psychotraumatol. 2025 Dec;16(1):2545048. doi: 10.1080/20008066.2025.2545048. Epub 2025 Sep 2.
Previous trials have demonstrated that Written Exposure Therapy (WET) is effective in treating post-traumatic stress disorder (PTSD), achieving comparable outcomes to more time-intensive treatments such as prolonged exposure and cognitive processing therapy, but with lower dropout rates. Its short duration, absence of between-session homework, and high adherence rates make WET a promising alternative to traditional more time-intensive therapy. Despite established efficacy of WET in controlled trials, questions remain about its feasibility, tolerability, and flexibility when implemented in routine psychiatric outpatient settings. This study addresses these gaps. Twenty-four patients, most with moderate to severe PTSD and significant psychiatric comorbidities, were recruited from a specialised psychiatric outpatient clinic for PTSD and underwent WET over a five-to-six-week period. Feasibility was assessed in terms of adherence, client satisfaction, adverse events, effectiveness, time requirements, and flexibility. PTSD symptom severity was measured at baseline, post-treatment, and one-month follow-up using the PTSD Checklist for DSM-5. The treatment was delivered either through face-to-face sessions at the clinic ( = 7) or via video conferencing ( = 15), with two participants receiving a combination of formats. Adherence was high, with 23 of 24 participants completed treatment. Client satisfaction was excellent, with a mean score of 25.91 (SD = 4.27) on the Client Satisfaction Questionnaire. Average therapist time required was under six hours per patient. Within-group analyses showed significant reductions in PTSD symptoms at one-month follow-up = 1.08, 95% CI: 0.47-1.69). No serious adverse events were reported. WET was feasible, resource-efficient, video-compatible, and suitable for delivery by individual therapists with limited training. WET proved to be a feasible, effective, and resource-efficient intervention for PTSD in routine psychiatric care. Its implementation may expand access to evidence-based treatment and reduce reliance on full-dose CBT. Further research should explore its role in optimising care pathways and addressing waiting lists. ClinicalTrials.gov identifier: NCT04328935.
先前的试验表明,书面暴露疗法(WET)在治疗创伤后应激障碍(PTSD)方面是有效的,其治疗效果与延长暴露疗法和认知加工疗法等耗时更长的治疗方法相当,但脱落率更低。WET疗程短、无需在疗程之间布置作业且依从率高,这使其成为传统耗时更长疗法的一个有前景的替代方案。尽管WET在对照试验中的疗效已得到证实,但在常规精神科门诊环境中实施时,其可行性、耐受性和灵活性仍存在疑问。本研究填补了这些空白。从一家专门的PTSD精神科门诊招募了24名患者,大多数患者患有中度至重度PTSD且伴有严重的精神共病,这些患者在五到六周的时间里接受了WET治疗。从依从性、患者满意度、不良事件、有效性、时间要求和灵活性等方面评估了可行性。使用《精神疾病诊断与统计手册》第5版创伤后应激障碍检查表在基线、治疗后和1个月随访时测量PTSD症状严重程度。治疗通过在诊所进行面对面治疗(n = 7)或通过视频会议(n = 15)进行,两名参与者接受了两种形式的组合。依从性很高,24名参与者中有23名完成了治疗。患者满意度很高,在患者满意度问卷上的平均得分为25.91(标准差 = 4.27)。每位患者平均所需的治疗师时间不到6小时。组内分析显示,在1个月随访时PTSD症状有显著减轻(t = 1.08,95%置信区间:0.47 - 1.69)。未报告严重不良事件。WET是可行的、资源高效的、与视频兼容的,并且适合由受过有限培训的个体治疗师提供。在常规精神科护理中,WET被证明是一种可行、有效且资源高效的PTSD干预措施。其实施可能会扩大基于证据的治疗的可及性,并减少对全剂量认知行为疗法的依赖。进一步的研究应探索其在优化护理途径和解决候诊名单方面的作用。ClinicalTrials.gov标识符:NCT04328935。
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