Fontes Filipa, Morais Alberto Gudo, Nhampule Joaquina, Navarro Sara, Sitoe Narciso, Amisse Leonel, Tulsidás Satish, Lorenzoni Cesaltina, Carrilho Carla, Lunet Nuno
Abordagem de Lesões Pré-Cancerosas e Cancro Precoce - Centro de Investigação (CI-IPOP), Instituto Português de Oncologia do Porto (IPO-Porto) & Porto Comprehensive Cancer Center (Porto.CCC) & RISE@CI-IPOP (Rede de Investigação Em Saúde), Porto, Portugal.
Departamento de Ciências da Saúde Pública e Forenses e Educação Médica, Faculdade de Medicina, Universidade do Porto, Porto, Portugal.
Cancer Med. 2025 Sep;14(17):e71199. doi: 10.1002/cam4.71199.
A Radiotherapy Service (RS) started working in the Maputo Central Hospital (MCH), Mozambique, in August 2019. Here we describe its first 5 years of activity.
A total of 810 patients who underwent external radiotherapy between August 2019 and December 2023 were considered for the analysis. Sociodemographic and clinical data were retrieved from the RS database, and the MCH Cancer Registry was used to obtain cancer incidence data.
There was an increase in newly admitted patients each year, except in 2023 (161 in 2020, 188 in 2021, 238 in 2022, and 185 in 2023). Patients admitted in 2019 were more likely to be from Maputo city and to receive palliative radiotherapy. The proportion of patients starting radiotherapy within 12, 24, 36, and 48 months after diagnosis was 38.8%, 78.1%, 91.7%, and 96.6%, respectively. There was an increasing trend (p for trend < 0.001) in the proportion of patients admitted with cervical cancer over time (from 34.2% in 2019 to 46.0% in 2023). Differences in radiotherapy initiation within 12 months were observed according to treatment intent (42.6% for palliative vs. 36.9% for curative; p = 0.014) and cancer site (64.5% for rectal/anal cancer vs. 34.8%, 29.5%, and 37.0% for cervical, breast and prostate cancer patients, respectively; p < 0.001).
The RS-MCH improved access to radiotherapy for cancer patients, particularly those with cervical and breast cancers. Patients undergoing palliative treatment and those with anal/rectal cancers started radiotherapy earlier. Further research is needed to evaluate the impact of radiotherapy on mortality, survival, and in patient-centered outcomes.
2019年8月，莫桑比克马普托中心医院（MCH）的放射治疗服务（RS）开始运行。在此，我们描述其最初5年的活动情况。
对2019年8月至2023年12月期间接受外照射放疗的810例患者进行分析。社会人口统计学和临床数据从RS数据库中获取，MCH癌症登记处用于获取癌症发病率数据。
除2023年外，每年新入院患者数量均有所增加（2020年为161例，2021年为188例，2022年为238例，2023年为185例）。2019年入院的患者更有可能来自马普托市并接受姑息性放疗。诊断后12、24、36和48个月内开始放疗的患者比例分别为38.8%、78.1%、91.7%和96.6%。随着时间的推移，宫颈癌入院患者的比例呈上升趋势（趋势p<0.001）（从2019年的34.2%升至2023年的46.0%）。根据治疗目的（姑息性治疗为42.6%，根治性治疗为36.9%；p=0.014）和癌症部位（直肠/肛管癌为64.5%，宫颈癌、乳腺癌和前列腺癌患者分别为34.8%、29.5%和37.0%；p<0.001），观察到12个月内放疗开始情况存在差异。
MCH的RS改善了癌症患者，尤其是宫颈癌和乳腺癌患者获得放疗的机会。接受姑息治疗的患者以及肛管/直肠癌患者更早开始放疗。需要进一步研究以评估放疗对死亡率、生存率和以患者为中心的结局的影响。
