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1064纳米掺钕钇铝石榴石激光用于苏丹女性脱毛的疗效与安全性:对菲茨帕特里克IV - VI型皮肤的研究

Efficacy and safety of 1064 nm nd: YAG laser for hair removal in Sudanese women: A study on Fitzpatrick skin types IV-VI.

作者信息

Mahmoud Eslam E A, Elbasheer Osman Abdelmalik, Marouf Ali A S

机构信息

Khartoum Dermatology Teaching Hospital, Khartoum, Sudan.

International University of Africa, Khartoum, Sudan.

出版信息

Lasers Med Sci. 2025 Sep 2;40(1):349. doi: 10.1007/s10103-025-04606-5.

Abstract

This study investigated the efficacy and safety of Nd: YAG laser (1064 nm) hair removal in 55 Sudanese women with Fitzpatrick skin types IV, V, and VI. The primary objective was to evaluate the influence of skin type, fluence, age, and geographic location on the number of treatments required to achieve satisfactory hair reduction in the chin area. Treatment parameters, including fluence (25-40 J/cm²), spot size (10-12 mm), and pulse width (20-40 ms), were tailored to individual characteristics using the Cynosure Elite + Nd: YAG laser with sapphire contact cooling. Outcomes were assessed using clinical evaluation, pre- and post-treatment photographs, and a standardized 5-point hair density scale. Statistical analysis revealed that fluence significantly impacted outcomes (p = 0.039), with 25 J/cm² demonstrating effectiveness. Skin type, age, and geographic location were not significant factors (p > 0.05). No topical bleaching cream was used, and many participants reported improvement in skin tone. No adverse events or paradoxical hypertrichosis were observed. The study supports the safe and effective use of low-fluence 1064 nm Nd: YAG laser treatment for hair removal in darker skin types. Future research should examine long-term outcomes and broader treatment sites.

摘要

本研究调查了掺钕钇铝石榴石激光(1064纳米)对55名 Fitzpatrick皮肤分型为IV、V和VI型的苏丹女性进行脱毛的疗效和安全性。主要目的是评估皮肤类型、能量密度、年龄和地理位置对下巴区域实现满意的毛发减少所需治疗次数的影响。使用带有蓝宝石接触式冷却的赛诺秀精英+掺钕钇铝石榴石激光,根据个体特征调整治疗参数,包括能量密度(25-40焦/平方厘米)、光斑大小(10-12毫米)和脉冲宽度(20-40毫秒)。使用临床评估、治疗前后照片以及标准化的5分毛发密度量表评估结果。统计分析显示,能量密度对结果有显著影响(p = 0.039),25焦/平方厘米显示出有效性。皮肤类型、年龄和地理位置不是显著因素(p > 0.05)。未使用外用漂白霜,许多参与者报告肤色有所改善。未观察到不良事件或矛盾性多毛症。该研究支持低能量密度1064纳米掺钕钇铝石榴石激光治疗在较深肤色类型脱毛中的安全有效应用。未来的研究应检查长期结果和更广泛的治疗部位。

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