延缓椎间盘退变的新方向：白藜芦醇抑制髓核细胞铁死亡 - Suppr

A New Direction for Delaying Intervertebral Disc Degeneration: Resveratrol Inhibits Ferroptosis in Nucleus Pulposus Cells.

作者信息

Wang Hong, Li Feilong, Mei Yongliang, Wu Taotao, Wang Liquan, Hao Pandeng, Ci Shenjing, Liu Zongchao

机构信息

The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, 646000, Sichuan, China.

Department of Orthopedics, Xuyong County People's Hospital, Luzhou, 646000, Sichuan, China.

出版信息

Cell Biochem Biophys. 2025 Sep 2. doi: 10.1007/s12013-025-01874-4.

DOI:10.1007/s12013-025-01874-4

PMID:40892370

Abstract

摘要

相似文献

A New Direction for Delaying Intervertebral Disc Degeneration: Resveratrol Inhibits Ferroptosis in Nucleus Pulposus Cells.

Cell Biochem Biophys. 2025 Sep 2. doi: 10.1007/s12013-025-01874-4.

Targeting Ferroptosis With Ginsenoside Rg3 Alleviates Intervertebral Disc Degeneration.

Orthop Surg. 2025 Aug 25. doi: 10.1111/os.70150.

Ferulic acid/GRB2/NF-κB signaling pathway that alleviates ferroptosis-induced apoptosis of nucleus pulposus cells is a potential mechanism for intervertebral disc degeneration.

J Orthop. 2025 Jun 21;65:302-309. doi: 10.1016/j.jor.2025.06.013. eCollection 2025 Jul.

Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-κB inflammatory pathway.

J Orthop Translat. 2023 May 5;40:13-26. doi: 10.1016/j.jot.2023.04.003. eCollection 2023 May.

Cynarin alleviates intervertebral disc degeneration via protecting nucleus pulposus cells from ferroptosis.

Biomed Pharmacother. 2023 Sep;165:115252. doi: 10.1016/j.biopha.2023.115252. Epub 2023 Aug 1.

Hesperidin mitigates oxidative stress-induced ferroptosis in nucleus pulposus cells via Nrf2/NF-κB axis to protect intervertebral disc from degeneration.

Cell Cycle. 2023 May;22(10):1196-1214. doi: 10.1080/15384101.2023.2200291. Epub 2023 Apr 13.

Duhuo Jisheng decoction alleviates intervertebral disc degeneration by inhibiting nucleus pulposus cell ferroptosis via the exosome-mediated miR-19b-3p/ACSL4 axis.

Phytomedicine. 2025 Oct;146:157113. doi: 10.1016/j.phymed.2025.157113. Epub 2025 Jul 30.

Fibro-NPC: a pathogenic subtype identified at single-cell resolution with secreted SFRP4 as a biomarker in intervertebral disc degeneration.

J Transl Med. 2025 Aug 6;23(1):867. doi: 10.1186/s12967-025-06798-4.

Injectable hydrogel loaded with exosomes from hypoxic umbilical cord-derived mesenchymal stem cells alleviates intervertebral disc degeneration by reversing nucleus pulposus cell senescence.

Regen Biomater. 2025 May 12;12:rbaf039. doi: 10.1093/rb/rbaf039. eCollection 2025.

Quercetin nanoformulation-embedded hydrogel inhibits osteopontin mediated ferroptosis for intervertebral disc degeneration alleviation.

J Nanobiotechnology. 2025 Jul 8;23(1):492. doi: 10.1186/s12951-025-03574-w.

本文引用的文献

Sangerbox: A comprehensive, interaction-friendly clinical bioinformatics analysis platform.

Imeta. 2022 Jul 8;1(3):e36. doi: 10.1002/imt2.36. eCollection 2022 Sep.

HIF-1α-induced expression of the m6A reader YTHDF1 inhibits the ferroptosis of nucleus pulposus cells by promoting SLC7A11 translation.

Aging Cell. 2024 Sep;23(9):e14210. doi: 10.1111/acel.14210. Epub 2024 May 23.

Inflammation Triggers Chondrocyte Ferroptosis in TMJOA via HIF-1α/TFRC.

J Dent Res. 2024 Jul;103(7):712-722. doi: 10.1177/00220345241242389. Epub 2024 May 20.

Lumbar intervertebral disc degeneration in low back pain.

Minerva Anestesiol. 2024 Apr;90(4):330-338. doi: 10.23736/S0375-9393.24.17843-1.

Bioinformatics-based discovery of intervertebral disc degeneration biomarkers and immune-inflammatory infiltrates.

JOR Spine. 2023 Dec 22;7(1):e1311. doi: 10.1002/jsp2.1311. eCollection 2024 Mar.

α-Ketoglutaric acid ameliorates intervertebral disk degeneration by blocking the IL-6/JAK2/STAT3 pathway.

Am J Physiol Cell Physiol. 2023 Oct 1;325(4):C1119-C1130. doi: 10.1152/ajpcell.00280.2023. Epub 2023 Sep 4.

A review of Duhuo Jisheng decoction mechanisms in intervertebral disc degeneration in vitro and animal studies.

J Orthop Surg Res. 2023 Jun 16;18(1):436. doi: 10.1186/s13018-023-03869-4.

The gut microbiota metabolite capsiate regulate SLC2A1 expression by targeting HIF-1α to inhibit knee osteoarthritis-induced ferroptosis.

Aging Cell. 2023 Jun;22(6):e13807. doi: 10.1111/acel.13807. Epub 2023 Mar 8.

Transferrin Receptor-Mediated Iron Uptake Promotes Colon Tumorigenesis.

Adv Sci (Weinh). 2023 Apr;10(10):e2207693. doi: 10.1002/advs.202207693. Epub 2023 Jan 26.

Multiple nano-drug delivery systems for intervertebral disc degeneration: Current status and future perspectives.

Bioact Mater. 2022 Nov 20;23:274-299. doi: 10.1016/j.bioactmat.2022.11.006. eCollection 2023 May.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

A New Direction for Delaying Intervertebral Disc Degeneration: Resveratrol Inhibits Ferroptosis in Nucleus Pulposus Cells.

作者信息

机构信息

出版信息

相似文献

本文引用的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

A New Direction for Delaying Intervertebral Disc Degeneration: Resveratrol Inhibits Ferroptosis in Nucleus Pulposus Cells.

作者信息

机构信息

出版信息

相似文献

本文引用的文献