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[肺泡石蜡沉着症:细支气管肺泡灌洗液体的细胞学和生物化学研究]

[Alveolar paraffinosis: cytologic and biochemical study of bronchiolo-alveolar lavage fluid].

作者信息

Dongay G, Levade T, Caratero A, Salvayre R, Lauque D, Carles P

出版信息

Rev Mal Respir. 1985;2(4):231-7.

PMID:4089299
Abstract

A case report of a diffuse alveolar lipoid pneumonia occurring in a patient incapable of giving a proper history underlines the diagnostic difficulty of lipoid pneumonias. Till now, unless the diagnosis was made at necropsy, one relied on a history of prolonged consumption of medications containing mineral oil, with evidence on open lung biopsy of excess fatty material in the pulmonary parenchyma. Chromatography on thin slices of the lipid extract of bronchiolo-alveolar lavage liquid fixed in silica gel, a simple technique, should rapidly give the diagnosis. In the alveolar form of the disease bronchopulmonary lavage returns a significant quantity of paraffin oil and may be considered as a therapeutic method.

摘要

一名无法提供确切病史的患者发生弥漫性肺泡类脂质性肺炎的病例报告凸显了类脂质性肺炎的诊断困难。到目前为止,除非在尸检时做出诊断,否则诊断依赖于长期服用含矿物油药物的病史,以及肺实质中存在过量脂肪物质的开胸肺活检证据。用硅胶固定的支气管肺泡灌洗液体脂质提取物在薄切片上进行色谱分析,这一简单技术应能迅速做出诊断。在疾病的肺泡型中,支气管肺灌洗会回收到大量石蜡油,可将其视为一种治疗方法。

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