Sady Maegan D, Coburn Shayna S, Kramer Zachary, Streisand Randi, Kahn Ilana
(current institution) Psychological Assessment Resources, Inc.
(prior, sponsor institution) Children's National Hospital, Washington, D.C.
Child Health Care. 2025 Jul-Sep;54(3):296-310. doi: 10.1080/02739615.2023.2259291. Epub 2023 Sep 21.
A strict gluten-free diet is the only treatment for celiac disease (CD), yet dietary adherence can be challenging for youth and may be impacted by the youth's executive functioning and attentional abilities. This study aimed to investigate whether attention and executive functioning (EF) were associated with dietary adherence in children with CD. Parents of 34 children (child age M(SD)=13.01(3.88), 56% female) from a multidisciplinary CD clinic completed ratings of attention and EF and dietary adherence. Parent-reported adherence was negatively correlated with behavioral regulation ( = -.52, < .01, = .27, 95% confidence interval (CI) [-.73, -.22]) and cognitive regulation ( = -.48, < .01, = .23, 95% CI [-.71, -.17]), with an interaction by age ( = .01, adjusted = .35, -0.15, 95% CI [-0.29, -0.07]) for behavior regulation. Youth who were rated as less adherent by their parents were rated as having more problems with behavioral (e.g., inhibition and self-monitoring) and cognitive regulation (e.g., planning, organization), and adolescents with lower parent-rated adherence were rated as having more problems with behavioral regulation in particular. Executive functioning deficits are an important treatment consideration for CD, particularly during adolescence.
严格的无麸质饮食是乳糜泻（CD）的唯一治疗方法，但对青少年来说，坚持饮食可能具有挑战性，并且可能受到青少年执行功能和注意力能力的影响。本研究旨在调查注意力和执行功能（EF）是否与CD患儿的饮食依从性相关。来自一个多学科CD诊所的34名儿童（儿童年龄M（标准差）=13.01（3.88），56%为女性）的父母完成了对注意力、EF和饮食依从性的评分。父母报告的依从性与行为调节（r = -.52，p <.01，R² = .27，95%置信区间[CI][-.73，-.22]）和认知调节（r = -.48，p <.01，R² = .23，95%CI[-.71，-.17]）呈负相关，行为调节存在年龄交互作用（r = .01，调整后R² = .35，β = -0.15，95%CI[-0.29，-0.07]）。被父母评为依从性较低的青少年在行为（如抑制和自我监控）和认知调节（如计划、组织）方面存在更多问题，尤其是父母评定依从性较低的青少年在行为调节方面存在更多问题。执行功能缺陷是CD治疗的一个重要考虑因素，尤其是在青少年时期。
