Liu Yuyan, Guo Xiao, Liu Panpan, Jia Shuying, Wang Fang, Li Fei, Yuan Ping, Wang Xuejing
Rehabilitation Medicine College, Shandong Second Medical University, Weifang, China.
Department of Cardio-Pulmonary Circulation, Innovation and Incubation Center (IIC), Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China.
Front Med (Lausanne). 2025 Aug 14;12:1659818. doi: 10.3389/fmed.2025.1659818. eCollection 2025.
Pulmonary hypertension (PH) is a significant global health challenge that profoundly impacts exercise tolerance and quality of life for affected individuals. While advancements in pharmacological therapies have improved symptom management, exercise capacity, and overall well-being, there is a growing recognition of rehabilitation therapy as a promising non-pharmacological approach. Rehabilitation therapy aims to restore or enhance physical, psychological, and social functioning in individuals compromised by disease, injury, or congenital conditions through an integrated approach encompassing medical, social, and educational interventions. In the context of PH, rehabilitation therapy encompasses diverse modalities, including exercise training, inspiratory muscle training, neuromuscular electrical stimulation, and psychological support. These interventions target key symptoms such as exercise intolerance and dyspnea, with the goal of improving patient outcomes and fostering a return to independent and meaningful living. Emerging evidence demonstrates that rehabilitation therapy is both safe and effective in enhancing cardiopulmonary function, muscle strength, and exercise capacity. Furthermore, it has been shown to alleviate anxiety and depression, improve quality of life, and facilitate reintegration into familial and social roles. This review provides a comprehensive overview of the clinical features, prevalence, and current treatment landscape of PH, with a particular focus on the role and advancements in rehabilitation therapy. We discuss the therapeutic potential of rehabilitation therapy in addressing the multifaceted challenges of PH and explore future directions and innovative approaches in this evolving field. By highlighting the clinical utility and research progress of rehabilitation therapy, this review aims to offer new insights and perspectives for optimizing the management of PH and improving patient outcomes.
肺动脉高压（PH）是一项重大的全球健康挑战，对受影响个体的运动耐量和生活质量产生深远影响。虽然药物治疗的进展改善了症状管理、运动能力和整体健康状况，但人们越来越认识到康复治疗是一种有前景的非药物方法。康复治疗旨在通过包括医疗、社会和教育干预的综合方法，恢复或增强因疾病、损伤或先天性疾病而受损的个体的身体、心理和社会功能。在PH的背景下，康复治疗包括多种方式，包括运动训练、吸气肌训练、神经肌肉电刺激和心理支持。这些干预针对运动不耐受和呼吸困难等关键症状，目标是改善患者预后并促进回归独立且有意义的生活。新出现的证据表明，康复治疗在增强心肺功能、肌肉力量和运动能力方面既安全又有效。此外，它已被证明可以减轻焦虑和抑郁，提高生活质量，并促进重新融入家庭和社会角色。本综述全面概述了PH的临床特征、患病率和当前治疗情况，特别关注康复治疗的作用和进展。我们讨论了康复治疗在应对PH多方面挑战方面的治疗潜力，并探索了这一不断发展领域的未来方向和创新方法。通过强调康复治疗的临床效用和研究进展，本综述旨在为优化PH管理和改善患者预后提供新的见解和观点。
