Leys D, Bourgeois P, Destée A, Petit H
Rev Neurol (Paris). 1985;141(6-7):499-500.
A twenty-nine year-old woman, with oral contraceptive medication over 10 years, was admitted with chorea and acute psychosis. Fourty-eight hours earlier she had initiated therapy with amphetamine. The mechanisms of these acute manifestations are discussed: oral contraceptives increase striatal post-synaptic dopaminergic sensitivity, while amphetamines facilitate the dopamine release in striatum.
一名29岁女性,服用口服避孕药超过10年,因舞蹈症和急性精神病入院。48小时前她开始使用苯丙胺进行治疗。本文讨论了这些急性表现的机制:口服避孕药会增加纹状体突触后多巴胺能敏感性,而苯丙胺会促进纹状体中的多巴胺释放。