Trouillas P, Brudon F, Saubier M
Rev Neurol (Paris). 1985;141(8-9):562-70.
Two patients with severe, repeated confusional episodes of apparent fluctuating dementia type, and electroencephalographic alterations (permanent, diffuse slow waves) on recordings, were found to have elevated parathormonemia and slightly raised or normal levels of calcemia. The only other sign of hyperparathyroidism was intermittent hypophosphoremia. Exploratory cervicotomy identified a parathyroid microadenoma in one case and a parathyroid adenoma in the other. Recovery of intellectual functions was slow but complete. The possible direct role of parathormone in the genesis of this parathyrotoxic encephalopathy is discussed.
两名患有严重、反复出现明显波动性痴呆类型的意识模糊发作且脑电图记录有改变(持续性弥漫性慢波)的患者,被发现甲状旁腺素血症升高,血钙水平略有升高或正常。甲状旁腺功能亢进的唯一其他迹象是间歇性低磷血症。探查性子宫颈切开术在一例中发现甲状旁腺微腺瘤,在另一例中发现甲状旁腺腺瘤。智力功能的恢复缓慢但完全。讨论了甲状旁腺素在这种甲状旁腺毒性脑病发生中的可能直接作用。