身体活动和体重指数对超重印度青少年健康相关生活质量的影响：一项随机对照研究。

Impact of physical activity and BMI on health-related quality of life in overweight Indian adolescents: A randomized controlled study.

作者信息

Srivastav Prateek, Vaishali K, Vinod Bhat H, Broadbent Suzanne

机构信息

Manipal College of Health Professions Manipal Department of Physiotherapy, Manipal, Karnataka, India.

Manipal College of Health Professions Department of Physiotherapy at Manipal, Manipal, Karnataka, India.

出版信息

Obes Pillars. 2025 Aug 16;16:100201. doi: 10.1016/j.obpill.2025.100201. eCollection 2025 Dec.

DOI:10.1016/j.obpill.2025.100201

PMID:40894181

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12397862/

Abstract

BACKGROUND

Health-related quality of life (HRQOL) is a critical yet often overlooked component of adolescent obesity management. While physical activity (PA) and body mass index (BMI) are established markers of health, their combined influence on HRQOL in Indian adolescents remains underexplored.

OBJECTIVE

To examine how PA and BMI influence overall and domain-specific HRQOL in overweight and adolescents with obesity following a structured lifestyle program.

METHODS

In this randomized controlled study, 604 adolescents (aged 11-16 years) with BMI above the 85th percentile were recruited from schools in Udupi, India. Individuals were randomized into three groups: multifactorial strategy (MFI: exercise, lifestyle education, behavioral counseling), exercise-only (EX), and Control group (CON). PA was measured using the Physical Activity Questionnaire for Adolescents (PAQ-A), and HRQOL was measured via the Pediatric Quality of Life Inventory (PedsQL 4.0). Linear mixed-effects models evaluated associations between PA, BMI, and HRQOL over a 12-month period, which included a 12-week intervention followed by 9 months of follow-up.

RESULTS

PA was linked with better HRQOL in the MFI (β = 9.30, p < 0.001) and EX (β = 4.47, p < 0.001) groups. Interestingly, higher BMI correlated with better HRQOL scores in both program arms. The CON group showed no meaningful association between PA and HRQOL. The domain-level analysis found that PA and BMI were positively linked to physical, emotional, social, and school functioning in both program groups, with more pronounced effects in the MFI group. The CON group showed improvement only in emotional functioning related to BMI.

CONCLUSION

Structured PA programs, especially those combining education and behavioral support, notably enhance the quality of life among overweight Indian adolescents. These findings reinforce the importance of focusing not solely on weight loss, but on holistic, behavior-driven health outcomes in adolescent obesity care.

CLINICAL TRIAL REGISTRATION

CTRI/2019/04/018,834.

摘要

背景

与健康相关的生活质量（HRQOL）是青少年肥胖管理中一个关键但常被忽视的组成部分。虽然身体活动（PA）和体重指数（BMI）是公认的健康指标，但它们对印度青少年HRQOL的综合影响仍未得到充分探索。

目的

研究在一个结构化生活方式项目之后，PA和BMI如何影响超重和肥胖青少年的总体及特定领域的HRQOL。

方法

在这项随机对照研究中，从印度乌度皮的学校招募了604名BMI高于第85百分位数的青少年（年龄11 - 16岁）。个体被随机分为三组：多因素策略组（MFI：运动、生活方式教育、行为咨询）、仅运动组（EX）和对照组（CON）。使用青少年身体活动问卷（PAQ - A）测量PA，通过儿童生活质量量表（PedsQL 4.0）测量HRQOL。线性混合效应模型评估了12个月期间PA、BMI和HRQOL之间的关联，这包括一个为期12周的干预，随后是9个月的随访。

结果

在MFI组（β = 9.30，p < 0.001）和EX组（β = 4.47，p < 0.001）中，PA与更好的HRQOL相关。有趣的是，在两个项目组中，较高的BMI都与更好的HRQOL得分相关。CON组中PA和HRQOL之间没有有意义的关联。领域水平分析发现，在两个项目组中，PA和BMI与身体、情感、社交和学校功能呈正相关，在MFI组中影响更显著。CON组仅在与BMI相关的情感功能方面有所改善。