De Francesco Pierpaolo, Vescovi Paolo, Feliciani Claudio, Iaria Roberta, Corcione Luigi, Giovannacci Ilaria
Department of Medicine and Surgery, University of Parma, Parma, Italy.
Case Rep Dent. 2025 Aug 22;2025:1229183. doi: 10.1155/crid/1229183. eCollection 2025.
The primary objective of the present study is the retrospective analysis of a clinical case of oral leishmaniasis treated at Parma Hospital and a review of the literature on mucosal leishmaniasis (ML) with oral cavity involvement. We report the case of a patient diagnosed in 2017 with mucocutaneous leishmaniasis who was referred to our clinic due to the emergence of oral manifestations. Through a detailed review of the clinical documentation, we aim to describe the clinical presentation, diagnosis, treatment choices made, and evolution of the disease. Literature describes various pharmacological approaches for leishmaniasis, with treatment selection dependent on clinical presentation. ML does not spontaneously resolve, and systemic therapy is necessary. Due to its rarity, oral leishmaniasis can be challenging to diagnose. This case report can help physicians recognize the clinical presentation of oral lesions, enabling prompt diagnosis and effective treatment.
本研究的主要目的是对帕尔马医院治疗的一例口腔利什曼病临床病例进行回顾性分析，并综述有关累及口腔的黏膜利什曼病（ML）的文献。我们报告了一例2017年被诊断为皮肤黏膜利什曼病的患者，因其出现口腔表现而转诊至我们的诊所。通过对临床记录的详细回顾，我们旨在描述该疾病的临床表现、诊断、所做的治疗选择以及病情演变。文献描述了利什曼病的各种药物治疗方法，治疗选择取决于临床表现。ML不会自行缓解，需要进行全身治疗。由于其罕见性，口腔利什曼病的诊断可能具有挑战性。本病例报告有助于医生认识口腔病变的临床表现，从而实现及时诊断和有效治疗。
