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Rapid beta-blocker up-titration enhances cardiac adrenergic innervation improvement in dilated cardiomyopathy.

作者信息

Dziewięcka Ewa, Holcman Katarzyna, Kostkiewicz Magdalena, Szot Wojciech, Wiśniowska-Śmiałek Sylwia, Winiarczyk Mateusz, Przytuła Natalia, Stępień-Wroniecka Agnieszka, Graczyk Katarzyna, Mazur Małgorzata, Leśniak-Sobelga Agata, Gąsiorek Jarosław, Czapska Agnieszka, Jamroś Jan, Garlicka Karolina, Rubiś Paweł

机构信息

Clinical Department of Cardiac and Vascular Diseases, Institute of Cardiology, Jagiellonian University Collegium Medicum, John Paul II Hospital, Prądnicka Street 80, 31-202 Krakow, Poland.

Department of Cardiac and Vascular Diseases, John Paul II Hospital, Prądnicka Street 80, 31-202 Krakow, Poland.

出版信息

Int J Cardiol Heart Vasc. 2025 Aug 25;60:101784. doi: 10.1016/j.ijcha.2025.101784. eCollection 2025 Oct.

DOI:10.1016/j.ijcha.2025.101784
PMID:40894345
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12398907/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5b6/12398907/4a1b86052819/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5b6/12398907/00b9627e2a81/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5b6/12398907/4a1b86052819/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5b6/12398907/00b9627e2a81/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5b6/12398907/4a1b86052819/gr1.jpg

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1
Rapid beta-blocker up-titration enhances cardiac adrenergic innervation improvement in dilated cardiomyopathy.快速上调β受体阻滞剂可增强扩张型心肌病患者心脏肾上腺素能神经支配的改善。
Int J Cardiol Heart Vasc. 2025 Aug 25;60:101784. doi: 10.1016/j.ijcha.2025.101784. eCollection 2025 Oct.
2
Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents.β受体阻滞剂治疗扩张型心肌病时的心肌基因表达
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3
Effect of the addition of a beta-blocker on left ventricular remodeling and prognosis in patients with dilated cardiomyopathy treated with angiotensin-converting enzyme inhibitor.在接受血管紧张素转换酶抑制剂治疗的扩张型心肌病患者中添加β受体阻滞剂对左心室重构及预后的影响。
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Recovery of the cardiac adrenergic nervous system after long-term beta-blocker therapy in idiopathic dilated cardiomyopathy: assessment by increase in myocardial 123I-metaiodobenzylguanidine uptake.特发性扩张型心肌病患者长期β受体阻滞剂治疗后心脏肾上腺素能神经系统的恢复：通过心肌123I-间碘苄胍摄取增加进行评估
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Association of beta-adrenergic receptor polymorphisms and progression to heart failure in patients with idiopathic dilated cardiomyopathy.特发性扩张型心肌病患者β-肾上腺素能受体基因多态性与心力衰竭进展的相关性
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[The relationship between the improvement of cardiac function and the myocardial uptake of I-123 metaiodobenzylguanidine in patients with dilated cardiomyopathy treated by beta-blocker].[β受体阻滞剂治疗扩张型心肌病患者心功能改善与I-123间碘苄胍心肌摄取的关系]
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Heart. 1998 Mar;79(3):256-61. doi: 10.1136/hrt.79.3.256.
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Adrenergic receptor genotype influences heart failure severity and β-blocker response in children with dilated cardiomyopathy.肾上腺素能受体基因型影响扩张型心肌病患儿的心衰严重程度及β受体阻滞剂反应。
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Therapy of idiopathic dilated cardiomyopathy with chronic beta-adrenergic blockade.慢性β-肾上腺素能阻滞剂治疗特发性扩张型心肌病
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本文引用的文献

1
The use of sacubitril/valsartan in different forms of heart failure.沙库巴曲缬沙坦在不同类型心力衰竭中的应用。
Int J Cardiol Heart Vasc. 2025 Mar 18;58:101650. doi: 10.1016/j.ijcha.2025.101650. eCollection 2025 Jun.
2
Temporal progression of replacement and interstitial fibrosis in optimally managed dilated cardiomyopathy patients: A prospective study.优化管理的扩张型心肌病患者的替换和间质纤维化的时间进程：一项前瞻性研究。
Int J Cardiol. 2024 Jul 15;407:131988. doi: 10.1016/j.ijcard.2024.131988. Epub 2024 Mar 27.
3
2023 ESC Guidelines for the management of cardiomyopathies.
2023年欧洲心脏病学会心肌病管理指南。
Eur Heart J. 2023 Oct 1;44(37):3503-3626. doi: 10.1093/eurheartj/ehad194.
4
2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure.2021年欧洲心脏病学会急性和慢性心力衰竭诊断与治疗指南。
Eur Heart J. 2021 Sep 21;42(36):3599-3726. doi: 10.1093/eurheartj/ehab368.
5
Multimodality imaging in the diagnosis, risk stratification, and management of patients with dilated cardiomyopathies: an expert consensus document from the European Association of Cardiovascular Imaging.多模态影像学在扩张型心肌病患者的诊断、风险分层和管理中的应用：欧洲心血管影像协会的专家共识文件。
Eur Heart J Cardiovasc Imaging. 2019 Oct 1;20(10):1075-1093. doi: 10.1093/ehjci/jez178.
6
Pathological evidence of adrenergic cardiac denervation in a patient with congestive heart failure.
Cardiovasc Pathol. 2018 Sep-Oct;36:20-21. doi: 10.1016/j.carpath.2018.05.007. Epub 2018 Jun 5.
7
Reverse remodeling in Dilated Cardiomyopathy: Insights and future perspectives.扩张型心肌病中的逆向重构：见解与未来展望。
Int J Cardiol Heart Vasc. 2018 Mar 8;18:52-57. doi: 10.1016/j.ijcha.2018.02.005. eCollection 2018 Mar.
8
ASNC imaging guidelines for SPECT nuclear cardiology procedures: Stress, protocols, and tracers.美国核医学与分子影像学会（ASNC）单光子发射计算机断层扫描（SPECT）核心脏病学检查的成像指南：负荷试验、方案及示踪剂
J Nucl Cardiol. 2016 Jun;23(3):606-39. doi: 10.1007/s12350-015-0387-x.
9
Significance of performing 123I-metaiodobenzylguanidine myocardial scintigraphy at different times for the long-term prediction of cardiac events in patients with dilated cardiomyopathy.123I-间碘苄胍心肌闪烁显像在不同时间进行对扩张型心肌病患者心脏事件长期预测的意义
Nucl Med Commun. 2010 Jun;31(6):488-94.
10
Cardiac sympathetic activity is associated with inflammation and neurohumoral activation in patients with idiopathic dilated cardiomyopathy.
Clin Physiol Funct Imaging. 2009 Nov;29(6):414-9. doi: 10.1111/j.1475-097X.2009.00887.x. Epub 2009 Jul 19.