Koenig Baudouin, Fitouchi Simon, Faucher Loïc, Jesel Laurence, Marzak Halim
Division of Cardiovascular Medicine, Nouvel Hôpital Civil, Strasbourg University Hospital, BP 426, Strasbourg 67091, France.
UR 3074 Translational CardioVascular Medicine, Centre de Recherche en Biomédecine de Strasbourg (CRBS), 1 Rue Eugène Boeckel, Strasbourg 67000, France.
Eur Heart J Case Rep. 2025 Aug 20;9(8):ytaf403. doi: 10.1093/ehjcr/ytaf403. eCollection 2025 Aug.
The number of transcatheter aortic valve replacement (TAVR) procedures is steadily increasing, and although its main complications are well documented, ventricular arrhythmias (VAs) following TAVR remain infrequently reported in the literature. We present a rare case of ventricular tachycardia (VT) occurring late after TAVR, originating from the lower portion of the prosthesis at the interventricular septum.
An 82-year-old Caucasian man presented with recurrent episodes of lipothymia and VT occurring late after undergoing TAVR. The VT persisted despite escalating medical therapy. He was referred for catheter ablation using a transseptal approach. Electroanatomical mapping of the left ventricle identified the earliest VT activation at the interventricular septum, adjacent to the lower portion of the prosthetic aortic valve. The arrhythmia was successfully treated with targeted radiofrequency ablation. At 11 months post-ablation, remote monitoring confirmed that the patient remained free of VT episodes.
This case report highlights a rare complication of TAVR. Clinicians should consider VT as a potential cause of presyncope or syncope following TAVR, rather than attributing these symptoms solely to conduction disorders. In this case, we demonstrate that catheter ablation targeting the interventricular septum near the lower portion of a 29-mm Edwards Sapien aortic valve was both feasible and effective.
经导管主动脉瓣置换术(TAVR)的手术数量正在稳步增加,尽管其主要并发症已有充分记录,但TAVR术后的室性心律失常(VA)在文献中仍鲜有报道。我们报告一例TAVR术后晚期发生的室性心动过速(VT)罕见病例,其起源于室间隔假体的下部。
一名82岁的白种男性在接受TAVR术后晚期出现反复发作的晕厥前期和VT。尽管药物治疗不断升级,但VT仍持续存在。他被转诊接受经房间隔途径的导管消融治疗。左心室的电解剖标测确定最早的VT激动位于室间隔,靠近人工主动脉瓣的下部。通过靶向射频消融成功治疗了心律失常。消融术后11个月,远程监测证实患者未再出现VT发作。
本病例报告突出了TAVR一种罕见的并发症。临床医生应将VT视为TAVR术后晕厥前期或晕厥的潜在原因,而不是将这些症状单纯归因于传导障碍。在本病例中,我们证明针对29毫米爱德华兹Sapien主动脉瓣下部附近的室间隔进行导管消融是可行且有效的。