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妊娠期间诊断为胸骨韧带样瘤切除术后使用生物基质进行胸壁重建的病例报告。

Case report of chest wall reconstruction using biological matrix following resection of a sternal desmoid tumor diagnosed in pregnancy.

作者信息

Walsh Jamie, Downes Amber, Brown Rachel, Walsh Ross, Geary Ellen, Quinlan Christine, Eaton Donna

机构信息

Department of Thoracic Surgery, Mater Misericordiae University Hospital Dublin, Eccles St, D07 R2WY, Ireland.

Department of Plastic Surgery, Mater Misericordiae University Hospital Dublin, Eccles St, D07 R2WY, Ireland.

出版信息

J Surg Case Rep. 2025 Aug 29;2025(8):rjaf548. doi: 10.1093/jscr/rjaf548. eCollection 2025 Aug.

Abstract

Desmoid tumors of the chest wall are rare and pose specific challenges in diagnosis, resection and reconstruction. While not known to have potential for metastasis, they have a high risk of recurrence following resection, even with negative margins. Adequate resection has the potential to leave large thoracic defects, the reconstruction of which are technically challenging and often require a multi-disciplinary surgical skill set. We present the case of a 34-year-old woman, diagnosed with desmoid tumor overlying the inferior aspect of her sternum during pregnancy. She underwent resection of the tumor along with the inferior sternum and costal cartilages and subsequent chest wall reconstruction with a biological porcine dermal collagen-based matrix patch (Permacol®) and myocutaneous reconstruction with a transposed, pedicled latissimus dorsi flap. This case demonstrates a novel technique for chest wall reconstruction highlights the complexities of managing these tumors during pregnancy and emphasizes the importance of a multidisciplinary surgical approach.

摘要

胸壁硬纤维瘤罕见,在诊断、切除和重建方面存在特殊挑战。虽然尚无转移潜能,但即使切缘阴性,切除后仍有很高的复发风险。充分切除可能会导致巨大的胸廓缺损,其重建在技术上具有挑战性,通常需要多学科的手术技能。我们报告一例34岁女性病例,该患者在孕期被诊断为胸骨下方的硬纤维瘤。她接受了肿瘤连同胸骨下部和肋软骨的切除,随后使用基于猪真皮胶原蛋白的生物基质补片(Permacol®)进行胸壁重建,并采用带蒂背阔肌肌皮瓣转移进行肌皮重建。本病例展示了一种胸壁重建的新技术,突出了孕期处理这些肿瘤的复杂性,并强调了多学科手术方法的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d85f/12396622/3f27eae52d58/rjaf548f1.jpg

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