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食管切除术后主动脉肠瘘的延迟表现。

Delayed presentation of aortoenteric fistula after esophagectomy.

作者信息

Shah Maya, Liu Peter H, Iglesias Nicholas, Lee Raphael, Livingstone Alan S

机构信息

University of Miami Miller School of Medicine, 1600 NW 10th Ave, Miami, FL 33136, United States.

Department of Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave, Miami, FL 33136, United States.

出版信息

J Surg Case Rep. 2025 Aug 29;2025(8):rjaf674. doi: 10.1093/jscr/rjaf674. eCollection 2025 Aug.

DOI:10.1093/jscr/rjaf674
PMID:40894948
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12394128/
Abstract

Aortoenteric fistula (AEF) is a rare but catastrophic complication following esophagectomy, often resulting in massive upper gastrointestinal bleeding and high mortality. While most cases occur early in the postoperative period, delayed presentations remain poorly understood. We report the case of a 54-year-old woman who underwent esophagectomy and gastric pull-up for mid-esophageal squamous cell carcinoma. Nine months postoperatively, the patient presented with hematemesis, hemorrhagic shock, and died despite resuscitative efforts. Autopsy revealed a 0.9 cm erosion in the descending thoracic aorta with adjacent ulceration of the gastric conduit and bacterial infiltration consistent with a thoracic AEF. This case illustrates a rare, delayed presentation of AEF confirmed by post-mortem analysis. It highlights the need for ongoing clinical vigilance even in patients with initially uncomplicated recoveries.

摘要

主动脉肠瘘(AEF)是食管切除术后一种罕见但灾难性的并发症,常导致大量上消化道出血和高死亡率。虽然大多数病例发生在术后早期,但延迟出现的情况仍了解甚少。我们报告一例54岁女性患者,因食管中段鳞状细胞癌接受了食管切除术和胃上提术。术后9个月,患者出现呕血、失血性休克,尽管进行了复苏努力仍死亡。尸检发现降主动脉有一处0.9厘米的糜烂,胃管道相邻处有溃疡,并有细菌浸润,符合胸段AEF。该病例说明了经尸检分析证实的AEF罕见的延迟表现。它强调即使是最初恢复未出现并发症的患者也需要持续的临床警惕。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5736/12394128/a4f8e80ea8c2/rjaf674f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5736/12394128/c04195c8f8d6/rjaf674f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5736/12394128/a4f8e80ea8c2/rjaf674f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5736/12394128/c04195c8f8d6/rjaf674f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5736/12394128/a4f8e80ea8c2/rjaf674f2.jpg

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本文引用的文献

1
Successful surgical treatment for aortoenteric fistula after esophagectomy: a case report.食管癌切除术后主动脉肠瘘的成功外科治疗:一例报告
Gen Thorac Cardiovasc Surg Cases. 2024 Jul 15;3(1):34. doi: 10.1186/s44215-024-00132-y.
2
Understanding Post-Esophagectomy Complications and Their Management: The Early Complications.了解食管切除术后并发症及其处理:早期并发症
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Intensive Surveillance After Esophagectomy in Patients with Esophageal Cancer: When, Why, and How Often?
Ann Surg Oncol. 2023 Apr;30(4):1948-1949. doi: 10.1245/s10434-022-12767-8. Epub 2022 Nov 13.
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Evaluation of postoperative surveillance strategies for esophago-gastric cancers in the UK and Ireland.英国和爱尔兰食管胃交界癌术后监测策略的评估。
Dis Esophagus. 2022 Feb 11;35(2). doi: 10.1093/dote/doab057.
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Erratum: Radiation therapy-induced aortoesophageal fistula: a case report and review of literature.勘误:放射治疗引起的主动脉食管瘘:一例报告并文献复习
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Resuscitative endovascular balloon occlusion of the aorta for uncontrollable nonvariceal upper gastrointestinal bleeding.经皮血管内球囊封堵主动脉术用于控制非静脉曲张性上消化道大出血
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Case Rep Surg. 2014;2014:614312. doi: 10.1155/2014/614312. Epub 2014 Dec 2.
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Thoracic endovascular aortic repair in management of aortoesophageal fistulas.胸主动脉腔内修复术治疗主动脉-食管瘘。
J Vasc Surg. 2014 Jan;59(1):248-54. doi: 10.1016/j.jvs.2013.07.117. Epub 2013 Nov 5.
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A clinical series of resuscitative endovascular balloon occlusion of the aorta for hemorrhage control and resuscitation.经导管主动脉球囊阻断术在出血控制和复苏中的临床系列研究。
J Trauma Acute Care Surg. 2013 Sep;75(3):506-11. doi: 10.1097/TA.0b013e31829e5416.
10
Gastroaortic fistula as an early complication of esophagectomy.胃主动脉瘘作为食管切除术后的早期并发症。
Ann Thorac Surg. 2001 Nov;72(5):1783-8. doi: 10.1016/s0003-4975(00)02569-8.