González-Hernández Cristina, Morenas-Aguilar Maria Dolores, Redondo Beatriz, Janicijevic Danica, López-Gómez María José, Vera Jesus, García-Ramos Amador
Department of Physical Education and Sport, Faculty of Sport Sciences, Universidad de Granada, Granada, Andalucía, Spain.
CLARO (Clinical and Laboratory Applications of Research in Optometry) Laboratory, Department of Optics, Faculty of Sciences, Universidad de Granada, Granada, Andalucía, Spain.
PeerJ. 2025 Aug 26;13:e19845. doi: 10.7717/peerj.19845. eCollection 2025.
This study aimed to compare intraocular pressure (IOP) responses during isometric handgrip strength tasks between primary open-angle glaucoma patients and healthy individuals.
Forty older adults participated: 21 glaucoma patients and 19 controls. Participants randomly performed four trials at two intensities, maximal and submaximal (at 50% of self-perceived maximal effort), with two trials per hand (one for the left eye and one for the right eye). IOP was measured immediately before exercise, during exercise, and 5 seconds post-recovery. A four-factor mixed ANOVA was used to analyze IOP responses, with task intensity and time of measurement as within-subject factors, and group (glaucoma vs. control) and sex as the between-subjects factors.
IOP responses were comparable between glaucoma patients and healthy individuals, as the main effect of group ( = 0.117) and its interactions did not reach statistical significance. The main effect of time reached statistical significance ( = 0.016) due to greater IOP values during the task (17.3 ± 3.7 mmHg) compared to pre-exercise (16.3 ± 3.2 mmHg: < 0.001), but post-exercise IOP (16.9 ± 4.1 mmHg) was not significantly different from pre-exercise ( = 0.334) or during exercise ( = 0.727). Greater IOP values were observed for the maximal task compared to the submaximal task ( = 0.001), with no differences between men and women ( = 0.699).
Submaximal isometric strength training is a safe option for glaucoma patients treated with hypotensive eye drops.
本研究旨在比较原发性开角型青光眼患者与健康个体在等长握力任务期间的眼压（IOP）反应。
40名老年人参与研究：21名青光眼患者和19名对照组。参与者在两种强度下随机进行四项试验，即最大强度和次最大强度（自我感知最大努力的50%），每只手进行两项试验（一只眼为左眼，另一只眼为右眼）。在运动前、运动期间和恢复后5秒测量眼压。采用四因素混合方差分析来分析眼压反应，任务强度和测量时间作为组内因素，组（青光眼与对照组）和性别作为组间因素。
青光眼患者与健康个体的眼压反应具有可比性，因为组的主效应（=0.117）及其相互作用未达到统计学显著性。时间的主效应达到统计学显著性（=0.016），因为与运动前（16.3±3.2 mmHg：<0.001）相比，任务期间眼压值更高（17.3±3.7 mmHg），但运动后眼压（16.9±4.1 mmHg）与运动前（=0.334）或运动期间（=0.727）无显著差异。与次最大任务相比，最大任务的眼压值更高（=0.001），男性和女性之间无差异（=0.699）。
次最大等长力量训练对于使用降眼压眼药水治疗的青光眼患者是一种安全的选择。
