上睑结膜毛囊角化性病变：一例报告
Trichilemmal Keratinized Lesion of the Upper Palpebral Conjunctiva: A Case Report.
作者信息
Papachristou Anastasia, Papandroudis Andreas, Lagoudaki Eleni, Detoraki Anna, Detorakis Efstathios T
机构信息
Department of Ophthalmology, University Hospital of Heraklion, Heraklion, GRC.
Department of Nursing, University of Thrace, Didimoteicho, GRC.
出版信息
Cureus. 2025 Jul 29;17(7):e88951. doi: 10.7759/cureus.88951. eCollection 2025 Jul.
OBJECTIVE
To present a case of keratinized lesion of the upper palpebral conjunctiva in a patient without prior ocular or systemic history.
METHODOLOGY
A case of keratinized lesion located at the upper palpebral conjunctiva in a 21-year-old female patient was managed at the Department of Ophthalmology of the University Hospital of Heraklion. Comprehensive clinical assessments, surgical excision, histopathological examinations, and relevant investigations were conducted to characterize the lesion and identify clinical and histological features. The patient was followed up for 12 months postoperatively.
RESULTS
Major presenting symptoms were ocular discomfort and conjunctival hyperemia. Histopathological examination was compatible with a cystic lesion with trichilemmal keratinization. No recurrence was observed during the follow-up period. Conclusions: Focal keratinization of diverse pathogenetic origin and histological appearance at the epithelium of the upper palpebral conjunctiva can be found in young patients without a previous history of trauma, surgery, or inflammation.
目的
报告一例无上睑结膜角化病变既往眼部或全身病史的患者。
方法
一名21岁女性患者上睑结膜出现角化病变，在伊拉克利翁大学医院眼科接受治疗。进行了全面的临床评估、手术切除、组织病理学检查及相关检查，以明确病变特征并确定临床和组织学特征。术后对患者进行了12个月的随访。
结果
主要症状为眼部不适和结膜充血。组织病理学检查结果与伴有外毛根鞘角化的囊性病变相符。随访期间未观察到复发情况。
结论
在上睑结膜上皮可发现病因多样、组织学表现各异的局灶性角化，此类情况可见于无创伤、手术或炎症既往史的年轻患者。
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