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一例动脉血pH值低于6.5的严重酸血症患者存活的病例报告。

A Case Report of a Patient Surviving Severe Acidemia With Arterial pH Less Than 6.5.

作者信息

Iyer Karthik V, Jebackumar Justin A, Sundet Sarah, Mathew Moye, Oke Vikram

机构信息

Internal Medicine/Critical Care Medicine, Mercy Hospital Jefferson, Festus, USA.

Internal Medicine, Lake Erie College of Osteopathic Medicine, Erie, USA.

出版信息

Cureus. 2025 Jul 31;17(7):e89135. doi: 10.7759/cureus.89135. eCollection 2025 Jul.

Abstract

Surviving an arterial pH below 6.5 is exceedingly rare due to significant disruption of processes at the cellular level. We report a case of a 25-year-old female with altered mental status, hypotension, and refractory metabolic acidosis. Initial arterial blood gases were unreadable, but aggressive sodium bicarbonate therapy revealed an arterial pH of 6.62. Suspected ethylene glycol poisoning led to aggressive bicarbonate replacement, fomepizole therapy, and emergent hemodialysis. The patient showed rapid clinical recovery and was discharged from the hospital after six days, demonstrating that recovery is possible with appropriate, timely care even at potentially fatal arterial pH levels.

摘要

由于细胞水平的过程受到严重破坏,动脉血pH值低于6.5时存活极为罕见。我们报告一例25岁女性病例,该患者有精神状态改变、低血压和难治性代谢性酸中毒。最初的动脉血气结果无法读取,但积极的碳酸氢钠治疗显示动脉血pH值为6.62。疑似乙二醇中毒导致积极的碳酸氢盐补充、甲吡唑治疗和紧急血液透析。患者临床恢复迅速,6天后出院,表明即使在潜在致命的动脉血pH值水平下,通过适当、及时的治疗也有可能康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bf3/12398339/68908569e3fc/cureus-0017-00000089135-i01.jpg

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