Du Zhongyuan, Chi Haojian, Li Xinge, Chen Daiwen, Pu Junning, Yu Bing
Key Laboratory of Animal Disease-Resistance Nutrition, Ministry of Education, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Anim Nutr. 2025 Jun 19;22:311-320. doi: 10.1016/j.aninu.2025.03.015. eCollection 2025 Sep.
Deoxynivalenol (DON) negatively affects the growth of piglets. Electron beam irradiation (EBI) has the potential to reduce the DON content in feeds. However, the quantitative effects of DON contamination and EBI on the nutritional value of corn remain unclear, as does the impact of this corn on piglet feeding. These experiments explored the effect of DON contamination and EBI treatment on the nutritional value of corn and the feeding effects of this corn on piglets. In Exp. 1, 40 piglets (initial weight: 14.88 ± 1.92 kg) were allotted to five experimental diets with eight replicates per diet. Five diets included four types of corn diets: normal corn (NC), DON-contaminated corn (DON-C), EBI-treated NC (EBI-NC), and EBI-treated DON-C (EBI-DON-C), and a nitrogen-free diet formulated to determine the basal endogenous loss of amino acids. In Exp. 2, 56 piglets (initial weight: 7.58 ± 0.35 kg) were randomly allocated to treatments arranged in a 2 × 2 factorial arrangement, with two types of corn (NC vs. DON-C) and two corn treatments (without EBI vs. EBI). There were four diets and seven replicate pens per diet, with two pigs per pen. The study found that both DON contamination and EBI treatment decreased the effective energy value of corn ( < 0.05), and EBI treatment also decreased the standardized ileal digestibility (SID) of most amino acids ( < 0.05), whereas DON contamination had no negative effect on the SID of amino acids (Exp. 1). In Exp. 2, EBI-treated corn (EBI-C) increased the average daily gain ( = 0.001) and average daily feed intake ( < 0.001), while increased feed conversion ratio (FCR) ( < 0.001) and decreased nutrient digestibility ( < 0.05). DON-C had a positive impact on FCR ( = 0.005). Neither EBI-C nor DON-C affected serum biochemical parameters ( > 0.05). However, DON-C may induce oxidative stress, impair immune function, and disrupt intestinal barrier. In conclusion, EBI reduced the DON content of DON-C, while impacted the nutritional value of corn. Furthermore, DON-C reduced the antioxidant capacity and immune function of piglets to some extent, although it did not affect their growth performance.
脱氧雪腐镰刀菌烯醇（DON）对仔猪生长有负面影响。电子束辐照（EBI）有降低饲料中DON含量的潜力。然而，DON污染和EBI对玉米营养价值的定量影响尚不清楚，这种玉米对仔猪饲养的影响也不清楚。这些实验探讨了DON污染和EBI处理对玉米营养价值的影响以及这种玉米对仔猪的饲养效果。在实验1中，40头仔猪（初始体重：14.88±1.92千克）被分配到五种实验日粮中，每种日粮有八个重复。五种日粮包括四种玉米日粮：正常玉米（NC）、受DON污染的玉米（DON-C）、经EBI处理的NC（EBI-NC）和经EBI处理的DON-C（EBI-DON-C），以及一种无氮日粮，用于确定氨基酸的基础内源性损失。在实验2中，56头仔猪（初始体重：7.58±0.35千克）被随机分配到按2×2析因设计安排的处理组中，有两种玉米（NC与DON-C）和两种玉米处理方式（无EBI与EBI）。有四种日粮，每种日粮有七个重复栏，每栏两头猪。研究发现，DON污染和EBI处理均降低了玉米的有效能值（P<0.05），EBI处理还降低了大多数氨基酸的标准回肠消化率（SID）（P<0.05），而DON污染对氨基酸的SID没有负面影响（实验1）。在实验2中，经EBI处理的玉米（EBI-C）提高了平均日增重（P = 0.001）和平均日采食量（P<0.001），同时提高了饲料转化率（FCR）（P<0.001）并降低了养分消化率（P<0.05）。DON-C对FCR有积极影响（P = 0.005）。EBI-C和DON-C均未影响血清生化参数（P>0.05）。然而，DON-C可能会诱导氧化应激、损害免疫功能并破坏肠道屏障。总之，EBI降低了DON-C中的DON含量，同时影响了玉米的营养价值。此外，DON-C在一定程度上降低了仔猪的抗氧化能力和免疫功能，尽管它没有影响它们的生长性能。
