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前哨淋巴结活检决策:外阴癌和宫颈癌淋巴结评估的当前证据与最佳实践

Sentinel Decisions: Current Evidence and Best Practices for Lymph Node Assessment in Vulvar and Cervical Cancers.

作者信息

Perinchery Malavika, Mills Kathryn

机构信息

University of Chicago Medical Center, Department of Obstetrics and Gynecology, United States.

University of Chicago Medical Center, Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, United States.

出版信息

Gynecol Oncol Rep. 2025 Jun 21;60:101786. doi: 10.1016/j.gore.2025.101786. eCollection 2025 Aug.

Abstract

Sentinel lymph node dissection (SLND) and biopsy has revolutionized the world of surgical oncology. SLND offers benefits such as decreased risk of lower extremity edema, lower infection rates and reduced blood loss. Many studies have explored the application of SLNB in the context of vulvar and cervical cancers. Evidence has demonstrated that it is a reasonable alternative to complete lymphadenectomy in the appropriate candidate. Furthermore, utilization of different dyes, such as ICG, has resulted in positive outcomes, resulting in shifts in practice. This review explores the current data and best practices for sentinel lymph node mapping and dissection in vulvar and cervical cancers.

摘要

前哨淋巴结清扫术(SLND)及活检彻底改变了外科肿瘤学领域。SLND具有诸多益处,如下肢水肿风险降低、感染率降低以及失血减少。许多研究探讨了前哨淋巴结活检(SLNB)在外阴癌和宫颈癌中的应用。有证据表明,对于合适的患者,它是完全淋巴结切除术的合理替代方案。此外,使用不同的染料,如吲哚菁绿(ICG),已取得了积极成果,从而导致了实践的转变。本综述探讨了外阴癌和宫颈癌前哨淋巴结定位及清扫的当前数据和最佳实践。

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