Alshahrani Saeed, Ali Majid, Alsreaya Rama, Najie Mohammed, Hijri Abdulrahman, Almalki Abdulrahman, Hassany Emad, Alhazmi Asma, Mirqami Bandar, Tawhari Faisal, Bajawi Yahya, Maashi Amirah, Ibrahim Ahmed, Alkazmeeni Ahmed, Alsreaya Aseel
Pharmaceutical Care Administration, Armed Forces Hospital Southern Region, Khamis Mushait, Saudi Arabia.
Department of Basic Sciences, Sulaiman Al-Rajhi University, Qassim, Saudi Arabia.
J Res Pharm Pract. 2025 Aug 7;14(2):50-58. doi: 10.4103/jrpp.jrpp_8_25. eCollection 2025 Apr-Jun.
This study evaluated pharmacists' and pharmacy technicians' knowledge, attitudes, and practices (KAPs) regarding pharmacovigilance and adverse drug reaction (ADR) reporting at a tertiary care facility in Saudi Arabia. It also sought to identify the barriers to ADR reporting and propose strategies to improve pharmacovigilance practices. This study is timely given recent initiatives by the Saudi Vision 2030 to strengthen medication safety practices nationwide.
A cross-sectional survey was conducted among pharmacists and pharmacy technicians at a tertiary care hospital in Saudi Arabia. A structured, self-administered questionnaire collected data on participants' KAPs regarding pharmacovigilance. Descriptive and inferential statistical analyses were conducted to identify the trends and associations between demographic variables and KAP scores.
A total of 200 healthcare professionals participated in the study. While 87% of participants were aware of pharmacovigilance and 91% were familiar with ADRs, only 47.5% had ever reported an ADR. Positive attitudes were observed, with 94% agreeing that ADR reporting is an essential role of pharmacists and 90% supporting its inclusion in pharmacy curricula. However, key barriers to ADR reporting included lack of time (65%), insufficient training (58%), and uncertainty about reporting procedures (49%). Significant associations were found between knowledge levels, age, gender, and educational qualifications ( < 0.05).
Despite high levels of knowledge and positive attitudes, ADR reporting practices remain suboptimal due to structural and procedural barriers. To enhance pharmacovigilance practices in Saudi Arabia, targeted training programs, simplified reporting systems, and mandatory reporting policies are recommended.
本研究评估了沙特阿拉伯一家三级医疗机构中药剂师和药房技术员关于药物警戒和药品不良反应（ADR）报告的知识、态度和实践（KAPs）。研究还旨在确定药品不良反应报告的障碍，并提出改善药物警戒实践的策略。鉴于沙特《2030年愿景》最近在全国加强药物安全实践的举措，本研究具有及时性。
在沙特阿拉伯一家三级医院对药剂师和药房技术员进行了横断面调查。通过一份结构化的自填问卷收集参与者关于药物警戒的知识、态度和实践的数据。进行描述性和推断性统计分析，以确定人口统计学变量与知识、态度和实践得分之间的趋势和关联。
共有200名医疗保健专业人员参与了该研究。虽然87%的参与者了解药物警戒，91%的参与者熟悉药品不良反应，但只有47.5%的人曾报告过药品不良反应。观察到积极的态度，94%的人同意药品不良反应报告是药剂师的一项重要职责，90%的人支持将其纳入药学课程。然而，药品不良反应报告的主要障碍包括缺乏时间（65%）、培训不足（58%）以及报告程序不明确（49%）。在知识水平、年龄、性别和教育程度之间发现了显著关联（<0.05）。
尽管知识水平较高且态度积极，但由于结构和程序障碍，药品不良反应报告实践仍未达到最佳状态。为加强沙特阿拉伯的药物警戒实践，建议开展有针对性的培训项目、简化报告系统并制定强制报告政策。
