Park Minwoo, Kim Sug Won, Kim Jiye
Department of Plastic and Reconstructive Surgery, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea.
Arch Craniofac Surg. 2025 Aug;26(4):160-164. doi: 10.7181/acfs.2025.0016. Epub 2025 Aug 20.
Keloids are benign fibroproliferative skin tumors that typically arise after cutaneous injuries, such as surgical incisions, burns, lacerations, tattoos, or infections. Malignant transformation of keloids is exceedingly rare, with only sporadic reports of squamous cell carcinoma. To date, sarcomatoid squamous cell carcinoma-an uncommon, highly aggressive squamous cell carcinoma variant-has not been described in association with keloidal scars. We present the first known case of sarcomatoid squamous cell carcinoma developing within a post‑acupuncture keloid scar, detailing its clinical presentation, histopathology, and surgical management. This report underscores the importance of malignancy screening in keloids displaying atypical features, particularly in trauma-exposed regions.
瘢痕疙瘩是一种良性纤维增生性皮肤肿瘤，通常在皮肤损伤后出现，如手术切口、烧伤、撕裂伤、纹身或感染。瘢痕疙瘩的恶性转化极为罕见，仅有散发性鳞状细胞癌的报道。迄今为止，尚未有关于肉瘤样鳞状细胞癌（一种罕见的、侵袭性很强的鳞状细胞癌变体）与瘢痕疙瘩性瘢痕相关的描述。我们报告了首例已知的在针灸后瘢痕疙瘩性瘢痕内发生肉瘤样鳞状细胞癌的病例，详细介绍了其临床表现、组织病理学和手术治疗情况。本报告强调了对表现出非典型特征的瘢痕疙瘩进行恶性筛查的重要性，尤其是在有创伤暴露的区域。
