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头皮微色素沉着术是治疗局限性脱发的有效方法：技术分析及十例病例报告系列

Scalp Micropigmentation Is an Effective Treatment for Localized Alopecia: Technical Analysis and a Series of Ten Case Reports.

作者信息

Liu Qinsi, Sun Mang, Zhang Jiezhi, Zhao Hengguang

机构信息

Department of Dermatology & Cosmetic Medicine Center, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

出版信息

J Cosmet Dermatol. 2025 Sep;24(9):e70375. doi: 10.1111/jocd.70375.

DOI:10.1111/jocd.70375
PMID:40899372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12406178/
Abstract

BACKGROUND

Scalp micropigmentation (SMP) is emerging for camouflaging localized alopecia, yet standardized protocols and long-term efficacy data remain limited.

AIMS

To evaluate technical parameters, clinical outcomes, and safety of SMP in diverse alopecia subtypes.

METHODS

Ten patients (androgenetic alopecia: n = 6; scarring alopecia: n = 4) underwent a standardized three-session SMP protocol. Technical refinements included zone-specific needle selection (single/triple point), hierarchical pigment deposition (prioritizing thick-haired regions), and randomized distribution to avoid uniformity. Pigment density was incrementally adjusted (30%→70%→100% of natural follicular spacing). Adherence to a zero-bleeding protocol ensured epidermal-upper dermal depth. Outcomes were assessed via visual density score (VDS, 010) and patient satisfaction score (PSS, 03).

RESULTS

All patients achieved significant cosmetic improvement. Immediate posttreatment VDS averaged 8.7 ± 1.1, with androgenetic cases scoring higher (9.1 ± 0.5). At 6-month follow-up, VDS declined modestly (7.7 ± 1.4), though scarring alopecia showed greater fading (Δ = 1.6 vs. Δ = 0.9 in androgenetic, p = 0.03). Patient satisfaction was high (mean PSS = 2.7/3), with 85.7% of androgenetic cases "very satisfied." Strong correlation existed between VDS and PSS (ρ = 0.91, p < 0.001). No adverse events occurred.

CONCLUSIONS

SMP is a safe, minimally invasive solution for localized alopecia, providing sustained cosmetic improvement. Technical refinements in needle selection, pigment layering, and depth control optimize outcomes. Future studies should focus on long-term pigment retention and expanded cohorts.

摘要

背景

头皮微色素沉着（SMP）正逐渐用于伪装局限性脱发，但标准化方案和长期疗效数据仍然有限。

目的

评估SMP在不同脱发亚型中的技术参数、临床结果和安全性。

方法

10例患者（雄激素性脱发：n = 6；瘢痕性脱发：n = 4）接受了标准化的三阶段SMP方案。技术改进包括特定区域的针头选择（单点/三点）、分层色素沉积（优先处理头发浓密区域）以及随机分布以避免均匀性。色素密度逐步调整（自然毛囊间距的30%→70%→100%）。坚持零出血方案确保表皮-真皮浅层深度。通过视觉密度评分（VDS，010）和患者满意度评分（PSS，03）评估结果。

结果

所有患者在外观上均有显著改善。治疗后即刻VDS平均为8.7±1.1，雄激素性脱发患者得分更高（9.1±0.5）。在6个月的随访中，VDS略有下降（7.7±1.4），尽管瘢痕性脱发褪色更明显（Δ = 1.6，而雄激素性脱发为Δ = 0.9，p = 0.03）。患者满意度较高（平均PSS = 2.7/3），85.7%的雄激素性脱发患者“非常满意”。VDS和PSS之间存在强相关性（ρ = 0.91，p < 0.001）。未发生不良事件。

结论

SMP是一种安全、微创的局限性脱发解决方案，可提供持续的外观改善。在针头选择、色素分层和深度控制方面的技术改进可优化结果。未来的研究应关注色素长期留存情况和扩大研究队列。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b433/12406178/71543e37dde3/JOCD-24-e70375-g005.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b433/12406178/b0846f934520/JOCD-24-e70375-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b433/12406178/78f56c9958a5/JOCD-24-e70375-g013.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b433/12406178/ecf44e4dc557/JOCD-24-e70375-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b433/12406178/2f88aa3c5376/JOCD-24-e70375-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b433/12406178/9887994b5d20/JOCD-24-e70375-g014.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b433/12406178/95a425d85ab4/JOCD-24-e70375-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b433/12406178/16d0f8c86880/JOCD-24-e70375-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b433/12406178/a8704b15a63b/JOCD-24-e70375-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b433/12406178/e1facadf0350/JOCD-24-e70375-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b433/12406178/df014d050237/JOCD-24-e70375-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b433/12406178/b0846f934520/JOCD-24-e70375-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b433/12406178/78f56c9958a5/JOCD-24-e70375-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b433/12406178/3933678541c3/JOCD-24-e70375-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b433/12406178/71543e37dde3/JOCD-24-e70375-g005.jpg

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