Pleskach V A, Bespalova M A, Tumanova S Iu, Ignatova T N
Tsitologiia. 1985 Nov;27(11):1304-7.
The concentration and composition of gangliosides in the cells of L-line and its clones--L-2 and Lebr 1/1, with values of saturation densities being 0.9, 1.6 and 3.2 X 10(5) cells/mc2, respectively, were compared. The transition of populations in the stationary growth phase was shown to be accompanied by an increment of ganglioside concentration and accumulation of di- and three-sialogangliosides. The data obtained are discussed in connection with the previously published results about changing intracellular cAMP content and conA-mediated agglutination at density-dependent growth inhibition L-cell variants.
比较了L系及其克隆L - 2和Lebr 1/1细胞中神经节苷脂的浓度和组成，其饱和密度值分别为0.9、1.6和3.2×10⁵个细胞/mc²。结果表明，处于稳定生长期的细胞群体转变伴随着神经节苷脂浓度的增加以及二唾液酸和三唾液酸神经节苷脂的积累。结合先前发表的关于密度依赖性生长抑制的L细胞变体中细胞内cAMP含量变化和刀豆蛋白A介导的凝集的结果，对所获得的数据进行了讨论。
