[低等灵长类动物和人类皮质类固醇代谢的比较特征]

[Comparative characteristics of corticosteroid metabolism in lower simians and man].

作者信息

Goncharov N P, Vorontsov V I

出版信息

Zh Evol Biokhim Fiziol. 1977 May-Jun;13(3):356-61.

Abstract

Corticosteroid metabolism has been investigated in Macaca mulatta, Papio hamadryas, Cercopithecus aethiops, Erithrocebus patas and man. Similar character of corticosteroid metabolism in monkeys and man was found. Significant interspecific differences with respect to quatitative and qualitative parameters of the metabolism of steroid hormones were found. In this respect M. mulatta and P. hamadryas are most similar to man as compared with other monkeys. These two species may be used as an adequate model in studies on human cortico-adrenal system.

摘要

已经对恒河猴、阿拉伯狒狒、埃塞俄比亚长尾猴、赤猴和人类的皮质类固醇代谢进行了研究。发现猴子和人类的皮质类固醇代谢具有相似特征。在类固醇激素代谢的定量和定性参数方面发现了显著的种间差异。在这方面，与其他猴子相比，恒河猴和阿拉伯狒狒与人类最为相似。这两个物种可作为研究人类皮质 - 肾上腺系统的合适模型。

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