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网膜附件炎:一种被忽视的急性腹痛病因。

Epiploic appendagitis: An overlooked cause of acute abdominal pain.

作者信息

El-Sawaf Yasser, Alzayani Salman, Saeed Nermin K, Bediwy Adel S, Elbeltagi Reem, Al-Roomi Khaldoon, Al-Beltagi Mohammed

机构信息

Department of Tropical Medicine, Faculty of Medicine, Tanta University, Tanta 31527, Alghrabia, Egypt.

Department of Gastroenterology, University Medical Center, King Abdulla Medical City, Arabian Gulf University, Manama 26671, Bahrain.

出版信息

World J Gastroenterol. 2025 Aug 28;31(32):109897. doi: 10.3748/wjg.v31.i32.109897.

DOI:10.3748/wjg.v31.i32.109897
PMID:40900773
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12400226/
Abstract

BACKGROUND

Epiploic appendagitis is a rare, often underrecognized cause of acute abdominal pain. Misdiagnosis can lead to unnecessary hospitalization, antibiotic use, or surgical intervention. Advances in imaging have improved the recognition of this self-limiting condition, but clinical awareness remains critical.

AIM

To provide a comprehensive update on the epidemiology, anatomy, pathogenesis, clinical presentation, diagnostic strategies, differential diagnosis, and management of epiploic appendagitis, emphasizing its distinguishing features from other causes of acute abdomen.

METHODS

A review of the literature was conducted, focusing on the clinical characteristics, imaging findings, differential diagnoses, and evidence-based management strategies for epiploic appendagitis.

RESULTS

Epiploic appendagitis typically presents with acute, localized, non-radiating abdominal pain without significant systemic symptoms. Diagnosis is heavily reliant on imaging, with computed tomography (CT) being the gold standard. Hallmark CT findings include a small, fat-density ovoid lesion adjacent to the colon, with the usual characteristic ring and dot signs. Differential diagnoses include mainly diverticulitis, appendicitis, omental infarction, and many other causes. Management is predominantly conservative with nonsteroidal anti-inflammatory drugs and observation, reserving surgical intervention for rare, complicated cases.

CONCLUSION

Recognizing the clinical and imaging features of epiploic appendagitis is essential to avoid unnecessary interventions. Increased clinician awareness, coupled with judicious use of imaging, facilitates timely diagnosis and appropriate management, ensuring optimal patient outcomes.

摘要

背景

网膜附件炎是一种罕见的、常未被充分认识的急性腹痛病因。误诊可导致不必要的住院、抗生素使用或手术干预。影像学的进展提高了对这种自限性疾病的认识,但临床意识仍然至关重要。

目的

全面更新网膜附件炎的流行病学、解剖学、发病机制、临床表现、诊断策略、鉴别诊断和管理,强调其与其他急腹症病因的区别特征。

方法

对文献进行综述,重点关注网膜附件炎的临床特征、影像学表现、鉴别诊断和循证管理策略。

结果

网膜附件炎通常表现为急性、局限性、无放射痛的腹痛,无明显全身症状。诊断严重依赖影像学检查,计算机断层扫描(CT)是金标准。CT的特征性表现包括结肠旁一个小的、脂肪密度的椭圆形病变,通常有特征性的环征和点征。鉴别诊断主要包括憩室炎、阑尾炎、网膜梗死和许多其他病因。治疗主要采用非甾体类抗炎药保守治疗并观察,对于罕见的复杂病例则采用手术干预。

结论

认识网膜附件炎的临床和影像学特征对于避免不必要的干预至关重要。临床医生意识的提高,加上合理使用影像学检查,有助于及时诊断和适当管理,确保患者获得最佳预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9806/12400226/83e4bd1a5b18/wjg-31-32-109897-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9806/12400226/27a6428efc5e/wjg-31-32-109897-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9806/12400226/fb0bb6b55d10/wjg-31-32-109897-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9806/12400226/9e649e2bb645/wjg-31-32-109897-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9806/12400226/83e4bd1a5b18/wjg-31-32-109897-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9806/12400226/27a6428efc5e/wjg-31-32-109897-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9806/12400226/fb0bb6b55d10/wjg-31-32-109897-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9806/12400226/9e649e2bb645/wjg-31-32-109897-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9806/12400226/83e4bd1a5b18/wjg-31-32-109897-g004.jpg

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本文引用的文献

1
Subacute Epiploic Appendagitis Masquerading as Left-Sided Abdominal Pain in an Elderly Female: A Rare Case Report.老年女性中表现为左侧腹痛的亚急性网膜附件炎:一例罕见病例报告
Clin Case Rep. 2025 Jan 31;13(2):e70167. doi: 10.1002/ccr3.70167. eCollection 2025 Feb.
2
Epiploic appendagitis on the vermiform appendix is often misdiagnosed as acute appendicitis.阑尾上的网膜性阑尾炎常被误诊为急性阑尾炎。
Emerg Radiol. 2025 Feb;32(1):131-135. doi: 10.1007/s10140-024-02304-3. Epub 2024 Dec 11.
3
Diverticulitis: A Review of Current and Emerging Practice-Changing Evidence.
憩室炎:当前及新出现的改变实践证据综述
Clin Colon Rectal Surg. 2023 Dec 13;37(6):359-367. doi: 10.1055/s-0043-1777439. eCollection 2024 Nov.
4
Epiploic Appendagitis: An Important Differential Diagnosis.网膜附件炎:一项重要的鉴别诊断
Cureus. 2024 Aug 25;16(8):e67750. doi: 10.7759/cureus.67750. eCollection 2024 Aug.
5
Epiploic Appendagitis: Systematic Review of a Distinctive Pathology.阑尾脂膜炎:一种独特病理学的系统综述。
Am Surg. 2024 Nov;90(11):3074-3081. doi: 10.1177/00031348241256062. Epub 2024 May 17.
6
Gynaecological Causes of Acute Pelvic Pain: Common and Not-So-Common Imaging Findings.急性盆腔疼痛的妇科病因:常见及不常见的影像学表现
Life (Basel). 2023 Oct 9;13(10):2025. doi: 10.3390/life13102025.
7
Primary Epiploic Appendagitis: Not Rare But Rarely Diagnosed Pathology.原发性阑尾脂膜炎:不罕见但却很少被诊断的病变。
Curr Med Imaging. 2023;19(11):1279-1285. doi: 10.2174/1573405619666230113122949.
8
Primary Epiploic Appendagitis of the Appendix Vermiformis.阑尾原发性类阑尾脂膜炎。
Curr Med Imaging. 2023;19(10):1207-1209. doi: 10.2174/1573405618666220816103122.
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Diagnostic Imaging and Medical Management of Acute Left-Sided Colonic Diverticulitis : A Systematic Review.急性左侧结肠憩室炎的诊断性影像学检查与医学管理:一项系统评价
Ann Intern Med. 2022 Mar;175(3):379-387. doi: 10.7326/M21-1645. Epub 2022 Jan 18.
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