Mehta Gaurav, Parmar Ajay, Shastri Minal, Patel Sahaj, Gandhi Vidhi, Karatela Shifa, Patel Apurva
Department of Medicine, Medical College Baroda, Vadodara, Gujarat, India.
Case Rep Med. 2025 Aug 25;2025:9925534. doi: 10.1155/carm/9925534. eCollection 2025.
Potassium is vital for cellular function, particularly in excitable tissues like nerves and muscles, which rely on potassium gradients to function normally. Hypokalemia can lead to severe issues such as muscle weakness and irregular heart rhythms. This case series presents four instances of hypokalemic paralysis, a neuromuscular condition that can be either periodic or isolated. The cases vary in presentation and treatment approach, highlighting the need to differentiate between primary and secondary causes of hypokalemia for optimal management. Fast and accurate diagnosis through laboratory tests and history taking is critical, and while acute management is standard, preventive strategies depend on the underlying cause. Further research is needed to establish definitive guidelines for the prevention of hypokalemic paralysis.
钾对于细胞功能至关重要,特别是在神经和肌肉等可兴奋组织中,这些组织依赖钾离子梯度来正常运作。低钾血症可导致严重问题,如肌肉无力和心律不齐。本病例系列展示了4例低钾性麻痹病例,这是一种神经肌肉疾病,可为周期性或孤立性。这些病例在表现和治疗方法上各不相同,突出了区分低钾血症的原发性和继发性原因以进行最佳管理的必要性。通过实验室检查和病史采集进行快速准确的诊断至关重要,虽然急性处理是标准做法,但预防策略取决于潜在病因。需要进一步研究以建立预防低钾性麻痹的明确指南。